CD44 Polyclonal Antibody

Uniprot: P16070
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  • polyclonal antibody-Elabscience
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    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
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      Catalog number:E-AB-30829

      Synonyms:LHR,BA-1,CD 44,CD44,CD44 antigen,CD44 molecule (Indian blood group),CD44 molecule,CD44,CDw44,Cell surface glycoprotein CD44,chondroitin sulfate proteoglycan 8,CSPG8,ECMR-III,Epican,Extracellular matrix receptor III,GP90 lymphocyte homing/adhesion receptor,HCELL,hematopoietic cell E- and L-selectin ligand,Heparan sulfate proteoglycan,Hermes antigen,homing function and Indian blood group system,HSA,HUTCH-I,HUTCH1,Hyaluronate receptor,IN,INLU-related p80 Glycoprotein,MC56,MDU2,MDU3,MGC10468,MIC4,MUTCH1,PGP-1,PGP-I,PGP1,Phagocytic glycoprotein 1,Phagocytic glycoprotein I,Soluble CD44

      Size:
      • 20 μL
      • 60 μL
      • 120 μL
      • 200 μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H,M,R

      Applications: WB,IHC-p,IF,ELISA

      Lead Time: 2 daysWelcome to order from local distributors.

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      Overview

      Synonyms LHR,BA-1,CD 44,CD44,CD44 antigen,CD44 molecule (Indian blood group),CD44 molecule,CD44,CDw44,Cell surface glycoprotein CD44,chondroitin sulfate proteoglycan 8,CSPG8,ECMR-III,Epican,Extracellular matrix receptor III,GP90 lymphocyte homing/adhesion receptor,HCELL,hematopoietic cell E- and L-selectin ligand,Heparan sulfate proteoglycan,Hermes antigen,homing function and Indian blood group system,HSA,HUTCH-I,HUTCH1,Hyaluronate receptor,IN,INLU-related p80 Glycoprotein,MC56,MDU2,MDU3,MGC10468,MIC4,MUTCH1,PGP-1,PGP-I,PGP1,Phagocytic glycoprotein 1,Phagocytic glycoprotein I,Soluble CD44
      Swissprot P16070
      Source Rabbit
      Reactivity Human,Mouse,Rat
      Immunogen Synthesized peptide derived from human CD44 around the non-phosphorylation site of Ser706.
      Application WB,IHC-p,IF,ELISA
      Recommended dilution WB 1:500-2000, IHC 1:50-300, IF 1:50-1:200
      Concentration 1mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Membrane
      Tissue specificity Isoform 10 (epithelial isoform) is expressed by cells of epithelium and highly expressed by carcinomas. Expression is repressed in neuroblastoma cells.
      Isotype IgG
      Purification Affinity purification
      Conjugation Unconjugated
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
      Background Receptor for hyaluronic acid (HA). Mediates cell-cell and cell-matrix interactions through its affinity for HA, and possibly also through its affinity for other ligands such as osteopontin, collagens, and matrix metalloproteinases (MMPs). Adhesion with HA plays an important role in cell migration, tumor growth and progression. Also involved in lymphocyte activation, recirculation and homing, and in hematopoiesis. Altered expression or dysfunction causes numerous pathogenic phenotypes. Great protein heterogeneity due to numerous alternative splicing and post-translational modification events.

      Images

      Western Blot analysis of Hela cells using CD44 Polyclonal Antibody at dilution of 1:500.

      Immunohistochemistry of paraffin-embedded Mouse testis tissue using CD44 Polyclonal Antibody at dilution of 1:200.

      Immunofluorescence analysis of Rat lung tissue using CD44 Polyclonal Antibody at dilution of 1:200.

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