CDC42EP5 Polyclonal Antibody

Uniprot: Q6NZY7
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
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    >
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-30856

      Synonyms:Binder of Rho GTPase 3 like,Binder of Rho GTPases 3,BORG3,CDC42 effector protein (Rho GTPase binding) 5,CDC42 effector protein 5,CEP5

      Size:
      • 20 μL
      • 60 μL
      • 120 μL
      • 200 μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H,M

      Applications: WB,IHC-p,ELISA

      Lead Time: 7~10 daysWelcome to order from local distributors.

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      Overview

      Synonyms Binder of Rho GTPase 3 like,Binder of Rho GTPases 3,BORG3,CDC42 effector protein (Rho GTPase binding) 5,CDC42 effector protein 5,CEP5
      Swissprot Q6NZY7
      Source Rabbit
      Reactivity Human,Mouse
      Immunogen Synthesized peptide derived from the N-terminal region of human Cdc42EP5
      Application WB,IHC-p,ELISA
      Recommended dilution WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:40000
      Concentration 1mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Cytoplasm. Cytoskeleton. Membrane; extrinsic to membrane.
      Isotype IgG
      Purification Affinity purification
      Conjugation Unconjugated
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
      Background Cell division control protein 42 (CDC42), a small Rho GTPase, regulates the formation of F-actin-containing structures through its interaction with the downstream effector proteins. The protein encoded by this gene is a member of the Borg (binder of Rho GTPases) family of CDC42 effector proteins. Borg family proteins contain a CRIB (Cdc42/Rac interactive-binding) domain. They bind to CDC42 and regulate its function negatively. The encoded protein may inhibit c-Jun N-terminal kinase (JNK) independently of CDC42 binding. The protein may also play a role in septin organization and inducing pseudopodia formation in fibroblasts.CDC42EP5 (CDC42 Effector Protein 5) is a Protein Coding gene. Among its related pathways are CDK-mediated phosphorylation and removal of Cdc6 and ERK Signaling. GO annotations related to this gene include GTP-Rho binding. An important paralog of this gene is CDC42EP1.

      Images

      Western Blot analysis of Jurkat cells using Cdc42EP5 Polyclonal Antibody at dilution of 1:500.

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