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CDH12 Polyclonal Antibody

Cat:E-AB-19682
Manual MSDS

Price: $ 399

Price: $ 240

Price: $ 143

Price: $ 73

Size:
200μL 120μL 60μL 20μL
Quantity:
  • Host: Rabbit
  • Reactivity: Human; Mouse
  • Applications: IHC
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Product Details
Verified Samples Verified Samples in IHC:Human brain,Human ovarian cancer
Dilution

IHC 1:50-1:100

Western Blot Operation Guide
Clonality Polyclonal
Immunogen Synthetic peptide of human CDH12
Abbre CDH12
Synonyms Br cadherin;BR-cadherin;Brain cadherin;CAD12_HUMAN;cadherin 12 (N cadherin 2);Cadherin 12;Cadherin 12 precursor;Cadherin 12 type 2 (N cadherin 2);Cadherin 12 type 2;Cadherin neural type 2;Cadherin-12;CDH12;CDHB;FLJ34857;N cadherin 2;N-cadherin 2;Neural type cadherin 2;Neuronal cadherin 2
Swissprot
Cellular Localization Membrane
Concentration 1.74 mg/mL
Buffer PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Purification Method Antigen affinity purification
Research Areas Signal Transduction
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping Ice bag
background This gene encodes a type II classical cadherin of the cadherin superfamily. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate the mature cadherin protein. These integral membrane proteins mediate calcium-dependent cell-cell adhesion and are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a histidine-alanine-valine (HAV) cell adhesion recognition sequence specific to type I cadherins. This particular cadherin appears to be expressed specifically in the brain and its temporal pattern of expression would be consistent with a role during a critical period of neuronal development, perhaps specifically during synaptogenesis.