CDH12 Polyclonal Antibody
Price: $ 399
Price: $ 240
Price: $ 143
Price: $ 73
Size:
200μL
120μL
60μL
20μL
Quantity:
- Host: Rabbit
- Reactivity: Human; Mouse
- Applications: IHC
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Product Details
Verified Samples |
Verified Samples in IHC:Human brain,Human ovarian cancer |
Dilution |
IHC 1:50-1:100 Western Blot Operation Guide |
Clonality | Polyclonal |
Immunogen | Synthetic peptide of human CDH12 |
Abbre | CDH12 |
Synonyms | Br cadherin;BR-cadherin;Brain cadherin;CAD12_HUMAN;cadherin 12 (N cadherin 2);Cadherin 12;Cadherin 12 precursor;Cadherin 12 type 2 (N cadherin 2);Cadherin 12 type 2;Cadherin neural type 2;Cadherin-12;CDH12;CDHB;FLJ34857;N cadherin 2;N-cadherin 2;Neural type cadherin 2;Neuronal cadherin 2 |
Swissprot | |
Cellular Localization | Membrane |
Concentration | 1.74 mg/mL |
Buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
Purification Method | Antigen affinity purification |
Research Areas | Signal Transduction |
Conjugation | Unconjugated |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Shipping | Ice bag |
background | This gene encodes a type II classical cadherin of the cadherin superfamily. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate the mature cadherin protein. These integral membrane proteins mediate calcium-dependent cell-cell adhesion and are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a histidine-alanine-valine (HAV) cell adhesion recognition sequence specific to type I cadherins. This particular cadherin appears to be expressed specifically in the brain and its temporal pattern of expression would be consistent with a role during a critical period of neuronal development, perhaps specifically during synaptogenesis. |
Experiment Operation Video
Protocols
• Western Blot Guide
• Immunohistochemistry Guide for Slide-mounted Paraffin Sections
• Immunofluorescence Guide
• Immunohistochemistry Troubleshooting Tips
• Western Blot Troubleshooting Tips
• Immunofluorescence Troubleshooting Tips
• Comparison of Protein Separation Linear Range
• ImmunoPrecipitation Protocol