CDK5 Polyclonal Antibody

Uniprot : Q00535
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    <
    >
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-30868

      Synonyms:Cdk 5,Cdk5,CDK5,Cell division protein kinase 5,Crk6,Cyclin dependent kinase 5,Cyclin-dependent kinase 5,Protein kinase CDK5 splicing,PSSALRE,Serine threonine protein kinase PSSALRE,Serine/threonine-protein kinase PSSALRE,Tau protein kinase II catalytic subunit,TPKII catalytic subunit

      Size:
      • 20 μL
      • 60 μL
      • 120 μL
      • 200 μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H,M,R

      Applications: WB,IHC-p,ELISA

      Lead Time: 2 daysWelcome to order from local distributors.

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      Overview

      Synonyms Cdk 5,Cdk5,CDK5,Cell division protein kinase 5,Crk6,Cyclin dependent kinase 5,Cyclin-dependent kinase 5,Protein kinase CDK5 splicing,PSSALRE,Serine threonine protein kinase PSSALRE,Serine/threonine-protein kinase PSSALRE,Tau protein kinase II catalytic subunit,TPKII catalytic subunit
      Swissprot Q00535
      Source Rabbit
      Reactivity Human,Mouse,Rat
      Immunogen Synthesized peptide derived from human Cdk5 around the non-phosphorylation site of Tyr15.
      Application WB,IHC-p,ELISA
      Recommended dilution WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:5000
      Concentration 1mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Cytoplasm. Cell projection>lamellipodium. Cell projection>growth cone. In axonal growth cone with extension to the peripheral lamellipodia.
      Tissue specificity Isoform 1 is ubiquitously expressed. Accumulates in cortical neurons (at protein level). Isoform 2 has only been detected in testis, skeletal muscle, colon, bone marrow and ovary.
      Isotype IgG
      Purification Affinity purification
      Conjugation Unconjugated
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
      Background Probably involved in the control of the cell cycle. Interacts with D1 and D3-type G1 cyclins. Can phosphorylate histone H1, tau, MAP2 and NF-H and NF-M. Also interacts with p35 which activates the kinase.

      Images

      Western Blot analysis of HepG2 cells using Cdk5 Polyclonal Antibody at dilution of 1:500.

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