CEP135 Polyclonal Antibody

Uniprot: Q66GS9
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
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    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-30879

      Synonyms:centrosomal protein 135 kDa,centrosomal protein 135kDa,Centrosomal protein 4,Centrosomal protein of 135 kDa,centrosome protein 4,centrosome protein cep135,Cep135,CEP4,CP135

      Size:
      • 20μL
      • 60μL
      • 120μL
      • 200μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H,M

      Applications: WB,IHC-p,ELISA

      Lead Time: 7~10 daysWelcome to order from local distributors.

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      Overview

      Synonyms centrosomal protein 135 kDa,centrosomal protein 135kDa,Centrosomal protein 4,Centrosomal protein of 135 kDa,centrosome protein 4,centrosome protein cep135,Cep135,CEP4,CP135
      Swissprot Q66GS9
      Source Rabbit
      Reactivity Human,Mouse
      Immunogen Synthesized peptide derived from the C-terminal region of human CEP135
      Application WB,IHC-p,ELISA
      Recommended dilution WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:40000
      Concentration 1mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. During centriole biogenesis, it is concentrated within the proximal lumen of both parental centrioles and procentrioles.
      Isotype IgG
      Purification Affinity purification
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.02% sodium azide,0.5% BSA and 50% glycerol pH 7.4.
      Background This gene encodes a centrosomal protein, which acts as a scaffolding protein during early centriole biogenesis, and is also required for centriole-centriole cohesion during interphase. Mutations in this gene are associated with autosomal recessive primary microcephaly-8.CEP135 (Centrosomal Protein 135) is a Protein Coding gene. Diseases associated with CEP135 include Microcephaly 8, Primary, Autosomal Recessive and Autosomal Recessive Primary Microcephaly. Among its related pathways are Regulation of PLK1 Activity at G2/M Transition and Organelle biogenesis and maintenance. GO annotations related to this gene include microtubule binding and protein C-terminus binding. An important paralog of this gene is TSGA10.

      Images

      Western Blot analysis of COLO cells using CEP135 Polyclonal Antibody at dilution of 1:1000.

      Western Blot analysis of Mouse lung, Mouse heart, 293T using CEP135 Polyclonal Antibody at dilution of 1:1000.

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