Synonyms:centrosomal protein 135 kDa,centrosomal protein 135kDa,Centrosomal protein 4,Centrosomal protein of 135 kDa,centrosome protein 4,centrosome protein cep135,Cep135,CEP4,CP135
|Synonyms||centrosomal protein 135 kDa,centrosomal protein 135kDa,Centrosomal protein 4,Centrosomal protein of 135 kDa,centrosome protein 4,centrosome protein cep135,Cep135,CEP4,CP135|
|Immunogen||Synthesized peptide derived from the C-terminal region of human CEP135|
|Recommended dilution||WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:40000|
|Cellular localization||Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. During centriole biogenesis, it is concentrated within the proximal lumen of both parental centrioles and procentrioles.|
|Storage instructions||Store at -20℃. Avoid freeze / thaw cycles.|
|Storage buffer||PBS with 0.02% sodium azide,0.5% BSA and 50% glycerol pH 7.4.|
|Background||This gene encodes a centrosomal protein, which acts as a scaffolding protein during early centriole biogenesis, and is also required for centriole-centriole cohesion during interphase. Mutations in this gene are associated with autosomal recessive primary microcephaly-8.CEP135 (Centrosomal Protein 135) is a Protein Coding gene. Diseases associated with CEP135 include Microcephaly 8, Primary, Autosomal Recessive and Autosomal Recessive Primary Microcephaly. Among its related pathways are Regulation of PLK1 Activity at G2/M Transition and Organelle biogenesis and maintenance. GO annotations related to this gene include microtubule binding and protein C-terminus binding. An important paralog of this gene is TSGA10.|
Western Blot analysis of COLO cells using CEP135 Polyclonal Antibody at dilution of 1:1000.
Western Blot analysis of Mouse lung, Mouse heart, 293T using CEP135 Polyclonal Antibody at dilution of 1:1000.