CEP170 Polyclonal Antibody

Uniprot: Q5SW79
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    <
    >
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-30881

      Synonyms:XRCC5 binding protein,4933426L22Rik,A330004A13Rik,AI195353,Centrosomal protein 170kDa,Cep170,FAM68A,KAB,KARP 1 binding protein,KARP1 binding protein,KIAA0470

      Size:
      • 20 μL
      • 60 μL
      • 120 μL
      • 200 μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H

      Applications: WB,IHC-p,ELISA

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      Overview

      Synonyms XRCC5 binding protein,4933426L22Rik,A330004A13Rik,AI195353,Centrosomal protein 170kDa,Cep170,FAM68A,KAB,KARP 1 binding protein,KARP1 binding protein,KIAA0470
      Swissprot Q5SW79
      Source Rabbit
      Reactivity Human
      Immunogen Synthesized peptide derived from the Internal region of human CEP170
      Application WB,IHC-p,ELISA
      Recommended dilution WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:40000
      Concentration 1mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Centrosome, centriole. Cytoplasm, cytoskeleton. Associated with the mature mother centriole. Associated with spindle microtubules during mitosis.
      Isotype IgG
      Purification Affinity purification
      Conjugation Unconjugated
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
      Background The product of this gene is a component of the centrosome, a non-membraneous organelle that functions as the major microtubule-organizing center in animal cells. During interphase, the encoded protein localizes to the sub-distal appendages of mature centrioles, which are microtubule-based structures thought to help organize centrosomes. During mitosis, the protein associates with spindle microtubules near the centrosomes. The protein interacts with and is phosphorylated by polo-like kinase 1, and functions in maintaining microtubule organization and cell morphology. The human genome contains a putative transcribed pseudogene. Several alternatively spliced transcript variants of this gene have been found, but the full-length nature of some of these variants has not been determined.

      Images

      Western Blot analysis of various cells using CEP170 Polyclonal Antibody at dilution of 1:1000.

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