CFC1 Polyclonal Antibody

Uniprot : P0CG37
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
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    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-17714

      Synonyms:CFC 1,CFC1,CFC1,CFC1B,CR 1,Cripto 1,Cripto FRL 1 cryptic family 1,CRYPTIC,Cryptic family 1,Cryptic family protein 1,Cryptic gene,Cryptic protein,DTGA2,FLJ77897,FRL 1,Heterotaxy 2 (autosomal dominant),HTX2,MGC133213

      Size:
      • 20μL
      • 60μL
      • 120μL
      • 200μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H

      Applications: IHC,ELISA

      Lead Time: 7~10 daysWelcome to order from local distributors.

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      Overview

      Synonyms CFC 1,CFC1,CFC1,CFC1B,CR 1,Cripto 1,Cripto FRL 1 cryptic family 1,CRYPTIC,Cryptic family 1,Cryptic family protein 1,Cryptic gene,Cryptic protein,DTGA2,FLJ77897,FRL 1,Heterotaxy 2 (autosomal dominant),HTX2,MGC133213
      Swissprot P0CG37
      Source Rabbit
      Reactivity Human
      Immunogen Synthetic peptide of human CFC1
      Application IHC(Detection kit: E-IR-R213),ELISA
      Recommended dilution IHC 1:25-100, ELISA 1:2000-5000
      Concentration 0.9 mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Cell membrane. Secreted. Does not exhibit a typical GPI-signal sequence. The C-ter hydrophilic extension of the GPI-signal sequence reduces the efficiency of processing and could lead to the production of an secreted unprocessed form. This extension is found only in primates.
      Isotype IgG
      Purification Affinity purification
      Conjugation Unconjugated
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
      Background This gene encodes a member of the epidermal growth factor (EGF)- Cripto, Frl-1, and Cryptic (CFC) family, which are involved in signalling during embryonic development. Proteins in this family share a variant EGF-like motif, a conserved cysteine-rich domain, and a C-terminal hydrophobic region. The protein encoded by this gene is necessary for patterning the left-right embryonic axis. Mutations in this gene are associated with defects in organ development, including autosomal visceral heterotaxy and congenital heart disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

      Images

      Immunohistochemistry of paraffin-embedded Human liver cancer tissue using CFC1 Polyclonal Antibody at dilution 1:30

      Immunohistochemistry of paraffin-embedded Human prostate cancer tissue using CFC1 Polyclonal Antibody at dilution 1:30

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