CFTR Polyclonal Antibody

Uniprot : P13569
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
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    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-30902

      Synonyms:ABC 35,ABC35,ABCC 7,ABCC7,ATP binding cassette sub family C member 7,ATP Binding Cassette Superfamily C Member 7,ATP binding cassette transporter sub family C member 7,ATP-binding cassette sub-family C member 7,cAMP dependent chloride channel,cAMP-dependent chloride channel,CF,CFTR,CFTR/MRP,CFTR,Channel conductance controlling ATPase,Channel conductance-controlling ATPase,Cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub family C,member 7),Cystic fibrosis transmembrane conductance regulator,Cystic fibrosis transmembrane conductance regulator ATP binding cassette sub family C member 7,Cystic Fibrosis Transmembrane Regulator,dJ760C5.1,MRP 7,MRP7,TNR CFTR

      Size:
      • 20 μL
      • 60 μL
      • 120 μL
      • 200 μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H,M,R

      Applications: WB,IHC-p,ELISA

      Lead Time: 2 daysWelcome to order from local distributors.

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      Overview

      Synonyms ABC 35,ABC35,ABCC 7,ABCC7,ATP binding cassette sub family C member 7,ATP Binding Cassette Superfamily C Member 7,ATP binding cassette transporter sub family C member 7,ATP-binding cassette sub-family C member 7,cAMP dependent chloride channel,cAMP-dependent chloride channel,CF,CFTR,CFTR/MRP,CFTR,Channel conductance controlling ATPase,Channel conductance-controlling ATPase,Cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub family C,member 7),Cystic fibrosis transmembrane conductance regulator,Cystic fibrosis transmembrane conductance regulator ATP binding cassette sub family C member 7,Cystic Fibrosis Transmembrane Regulator,dJ760C5.1,MRP 7,MRP7,TNR CFTR
      Swissprot P13569
      Source Rabbit
      Reactivity Human,Mouse,Rat
      Immunogen Synthesized peptide derived from human CFTR around the non-phosphorylation site of Ser737.
      Application WB,IHC-p,ELISA
      Recommended dilution WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:5000
      Concentration 1mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Early endosome membrane.
      Tissue specificity Found on the surface of the epithelial cells that line the lungs and other organs.
      Isotype IgG
      Purification Affinity purification
      Conjugation Unconjugated
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
      Background This gene encodes a member of the ATP-binding cassette (ABC) transporter superfamily. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily that is involved in multi-drug resistance. The encoded protein functions as a chloride channel and controls the regulation of other transport pathways. Mutations in this gene are associated with the autosomal recessive disorders cystic fibrosis and congenital bilateral aplasia of the vas deferens. Alternatively spliced transcript variants have been described, many of which result from mutations in this gene.

      Images

      Western Blot analysis of SH-SY5Y cells using CFTR Polyclonal Antibody at dilution of 1:2000.

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