CHOP Monoclonal Antibody

Uniprot : P35638
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    • monoclonal antibody-Elabscience
    • monoclonal antibody-Elabscience
    • monoclonal antibody-Elabscience
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    • monoclonal antibody-Elabscience
    • monoclonal antibody-Elabscience
    • monoclonal antibody-Elabscience
    • monoclonal antibody-Elabscience
    • monoclonal antibody-Elabscience
    • monoclonal antibody-Elabscience
    • monoclonal antibody-Elabscience
    • monoclonal antibody-Elabscience

      Catalog number:E-AB-22243

      Synonyms:C/EBP homologous protein,C/EBP Homology Protein,C/EBP zeta,C/EBP-homologous protein 10,C/EBP-homologous protein,CCAAT/enhancer binding protein homologous protein,CEBPZ,CHOP 10,CHOP,CHOP-10,CHOP10,DDIT 3,DDIT-3,Ddit3,DDIT3,DNA Damage Inducible Transcript 3,DNA damage-inducible transcript 3 protein,GADD 153,GADD153,Growth Arrest and DNA Damage Inducible Protein 153,Growth arrest and DNA damage inducible protein GADD153,Growth arrest and DNA damage-inducible protein GADD153,MGC4154

      Size:
      • 20μL
      • 60μL
      • 120μL
      • 200μL
      Qty:
      - +
      Price: $69

      Host: Mouse

      Reactivity: H,M,R

      Applications: IHC-p

      Lead Time: 7~10 daysWelcome to order from local distributors.

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      Overview

      Synonyms C/EBP homologous protein,C/EBP Homology Protein,C/EBP zeta,C/EBP-homologous protein 10,C/EBP-homologous protein,CCAAT/enhancer binding protein homologous protein,CEBPZ,CHOP 10,CHOP,CHOP-10,CHOP10,DDIT 3,DDIT-3,Ddit3,DDIT3,DNA Damage Inducible Transcript 3,DNA damage-inducible transcript 3 protein,GADD 153,GADD153,Growth Arrest and DNA Damage Inducible Protein 153,Growth arrest and DNA damage inducible protein GADD153,Growth arrest and DNA damage-inducible protein GADD153,MGC4154
      Swissprot P35638
      Source Mouse
      Reactivity Human,Mouse,Rat
      Immunogen Synthetic Peptide of CHOP
      Application IHC-p(Detection kit: E-IR-R217)
      Recommended dilution IHC 1:100-200
      Concentration 1 mg/mL
      Clonality Monoclonal

      Properties

      Cellular localization Nucleus.
      Clone No. Clone:1E1
      Isotype IgG
      Purification Protein A purification
      Conjugation Unconjugated
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
      Background This gene encodes a member of the CCAAT/enhancer-binding protein (C/EBP) family of transcription factors. The protein functions as a dominant-negative inhibitor by forming heterodimers with other C/EBP members, such as C/EBP and LAP (liver activator protein), and preventing their DNA binding activity. The protein is implicated in adipogenesis and erythropoiesis, is activated by endoplasmic reticulum stress, and promotes apoptosis. Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in myxoid liposarcomas or Ewing sarcoma. Multiple alternatively spliced transcript variants encoding two isoforms with different length have been identified. 

      Images

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      Immunohistochemistry of paraffin-embedded Human stomach carcinoma tissue using CHOP Monoclonal Antibody at dilution of 1:200.

      monoclonal antibody-Elabscience

      Immunohistochemistry of paraffin-embedded Human pancreas carcinoma tissue using CHOP Monoclonal Antibody at dilution of 1:200.

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