CK-20 Polyclonal Antibody

Uniprot : P35900
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
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    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-17668

      Synonyms:K20,CD20,CK20,CK-20,KRT21

      Size:
      • 20μL
      • 60μL
      • 120μL
      • 200μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H,M,R

      Applications: IHC,ELISA

      Lead Time: 7~10 daysWelcome to order from local distributors.

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      Overview

      Synonyms K20,CD20,CK20,CK-20,KRT21
      Swissprot P35900
      Source Rabbit
      Reactivity Human,Mouse,Rat
      Immunogen Synthetic peptide of human KRT20
      Application IHC,ELISA
      Recommended dilution IHC 1:25-100, ELISA 1:2000-5000
      Concentration 1 mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Cytoplasm
      Tissue specificity Expressed predominantly in the intestinal epithelium. Expressed in luminal cells of colonic mucosa. Also expressed in the Merkel cells of keratinized oral mucosa; specifically at the tips of some rete ridges of the gingival mucosa, in the basal layer of the palatal mucosa and in the taste buds of lingual mucosa.
      Isotype IgG
      Purification Affinity purification
      Conjugation Unconjugated
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
      Background The protein encoded by this gene is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. This cytokeratin is a major cellular protein of mature enterocytes and goblet cells and is specifically expressed in the gastric and intestinal mucosa. The type I cytokeratin genes are clustered in a region of chromosome 17q12-q21.

      Images

      Immunohistochemistry of paraffin-embedded Human liver cancer tissue using CK-20 Polyclonal Antibody at dilution 1:35

      Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using CK-20 Polyclonal Antibody at dilution 1:35

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