Claudin 6 Polyclonal Antibody

Uniprot : P56747
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    <
    >
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-30947

      Synonyms:Claudin-6,Claudin6,CLD6,CLDN 6,CLDN6,OTTHUMP00000159248,Skullin 2,Skullin,UNQ757/PRO1488

      Size:
      • 20μL
      • 60μL
      • 120μL
      • 200μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H

      Applications: WB,IHC-p,IF,ELISA

      Lead Time: 7~10 daysWelcome to order from local distributors.

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      Overview

      Synonyms Claudin-6,Claudin6,CLD6,CLDN 6,CLDN6,OTTHUMP00000159248,Skullin 2,Skullin,UNQ757/PRO1488
      Swissprot P56747
      Source Rabbit
      Reactivity Human
      Immunogen Synthesized peptide derived from the Internal region of human Claudin-6
      Application WB,IHC-p,IF,ELISA
      Recommended dilution WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:40000
      Concentration 1mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Cell junction>tight junction. Cell membrane.
      Tissue specificity Expressed in the liver, in peripheral blood mononuclear cells and hepatocarcinoma cell lines.
      Isotype IgG
      Purification Affinity purification
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.02% sodium azide,0.5% BSA and 50% glycerol pH 7.4.
      Background Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. This gene encodes a component of tight junction strands, which is a member of the claudin family. The protein is an integral membrane protein and is one of the entry cofactors for hepatitis C virus. The gene methylation may be involved in esophageal tumorigenesis. This gene is adjacent to another family member CLDN9 on chromosome 16.

      Images

      Western Blot analysis of Jurkat cells with Claudin 6 Polyclonal Antibody

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