CLCN6 Polyclonal Antibody

Uniprot: P51797
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
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    >
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-30949

      Synonyms:CLCN6,KIAA0046,Chloride transport protein 6,Chloride channel protein 6,ClC-6

      Size:
      • 20 μL
      • 60 μL
      • 120 μL
      • 200 μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H,M,R,Mk

      Applications: WB,ELISA

      Lead Time: 2 daysWelcome to order from local distributors.

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      Overview

      Synonyms CLCN6,KIAA0046,Chloride transport protein 6,Chloride channel protein 6,ClC-6
      Swissprot P51797
      Source Rabbit
      Reactivity Human,Mouse,Rat,Monkey
      Immunogen Synthesized peptide derived from the Internal region of human CLC-6
      Application WB,ELISA
      Recommended dilution WB 1:500-1:2000, ELISA 1:40000
      Concentration 1mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Endosome membrane,Lysosome,lysosomal membrane,Other locations:integral component of membrane
      Tissue specificity Testis, ovary, small intestine, brain and skeletal muscle. Low level expression in aortic and coronary vascular smooth muscle cells, and aortic endothelial cells. Isoform 3 is only detected in kidney.
      Isotype IgG
      Purification Affinity purification
      Conjugation Unconjugated
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
      Background This gene encodes a member of the voltage-dependent chloride channel protein family. Members of this family can function as either chloride channels or antiporters. This protein is primarily localized to late endosomes and functions as a chloride/proton antiporter. Alternate splicing results in both coding and non-coding variants. Additional alternately spliced variants have been described but their full-length structure is unknown.CLCN6 (Chloride Voltage-Gated Channel 6) is a Protein Coding gene. Diseases associated with CLCN6 include Benign Familial Infantile Epilepsy. Among its related pathways are Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds and HIV Life Cycle. GO annotations related to this gene include ion channel activity and voltage-gated chloride channel activity. An important paralog of this gene is CLCN7.

      Images

      Western Blot analysis of K562 cells using CLCN6 Polyclonal Antibody at dilution of 1:500.

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