CLCN7 Polyclonal Antibody

Uniprot: P51798
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
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    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-30950

      Synonyms:Chloride channel protein 7,CLC 7,ClC-7,ClC7,CLCN7,CLCN7,FLJ26686,FLJ39644,FLJ46423,H(+)/Cl(-) exchange transporter 7,OPTA2,OPTB4

      Size:
      • 20 μL
      • 60 μL
      • 120 μL
      • 200 μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H,M,R

      Applications: WB,ELISA

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      Overview

      Synonyms Chloride channel protein 7,CLC 7,ClC-7,ClC7,CLCN7,CLCN7,FLJ26686,FLJ39644,FLJ46423,H(+)/Cl(-) exchange transporter 7,OPTA2,OPTB4
      Swissprot P51798
      Source Rabbit
      Reactivity Human,Mouse,Rat
      Immunogen Synthesized peptide derived from the N-terminal region of human CLC-7
      Application WB,ELISA
      Recommended dilution WB 1:500-1:2000, ELISA 1:40000
      Concentration 1mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Lysosome membrane.
      Tissue specificity Brain, testis, muscle and kidney.
      Isotype IgG
      Purification Affinity purification
      Conjugation Unconjugated
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
      Background The product of this gene belongs to the CLC chloride channel family of proteins. Chloride channels play important roles in the plasma membrane and in intracellular organelles. This gene encodes chloride channel 7. Defects in this gene are the cause of osteopetrosis autosomal recessive type 4 (OPTB4), also called infantile malignant osteopetrosis type 2 as well as the cause of autosomal dominant osteopetrosis type 2 (OPTA2), also called autosomal dominant Albers-Schonberg disease or marble disease autosoml dominant. Osteopetrosis is a rare genetic disease characterized by abnormally dense bone, due to defective resorption of immature bone. OPTA2 is the most common form of osteopetrosis, occurring in adolescence or adulthood.

      Images

      Western Blot analysis of A549 cells using CLCN7 Polyclonal Antibody at dilution of 1:500.

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