CLK1 Polyclonal Antibody

Uniprot : P49759
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
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    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-30958

      Synonyms:CDC like kinase 1,CDC-like kinase 1,CDC28/CDC2 like kinase,CLK,CLK/STY,Clk1,CLK1,Dual specificity protein kinase CLK1,Protein tyrosine kinase STY,STY

      Size:
      • 20 μL
      • 60 μL
      • 120 μL
      • 200 μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H,M

      Applications: WB,IHC-p,IF,ELISA

      Lead Time: 2 daysWelcome to order from local distributors.

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      Overview

      Synonyms CDC like kinase 1,CDC-like kinase 1,CDC28/CDC2 like kinase,CLK,CLK/STY,Clk1,CLK1,Dual specificity protein kinase CLK1,Protein tyrosine kinase STY,STY
      Swissprot P49759
      Source Rabbit
      Reactivity Human,Mouse
      Immunogen Synthesized peptide derived from the Internal region of human CLK1
      Application WB,IHC-p,IF,ELISA
      Recommended dilution WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:20000
      Concentration 1mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Nucleus.
      Tissue specificity Endothelial cells.
      Isotype IgG
      Purification Affinity purification
      Conjugation Unconjugated
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
      Background This gene encodes a member of the CDC2-like (or LAMMER) family of dual specificity protein kinases. In the nucleus, the encoded protein phosphorylates serine/arginine-rich proteins involved in pre-mRNA processing, releasing them into the nucleoplasm. The choice of splice sites during pre-mRNA processing may be regulated by the concentration of transacting factors, including serine/arginine rich proteins. Therefore, the encoded protein may play an indirect role in governing splice site selection. Multiple transcript variants encoding different isoforms have been found for this gene.CLK1 (CDC Like Kinase 1) is a Protein Coding gene. Among its related pathways are mRNA Splicing - Major Pathway and Legionellosis. GO annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity. An important paralog of this gene is CLK4.

      Images

      Western Blot analysis of 293 cells using CLK1 Polyclonal Antibody at dilution of 1:500.

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