Cofilin Polyclonal Antibody

Uniprot : P23528,Q9Y281
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
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    >
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-30985

      Synonyms:CFL1,CFL,Cofilin-1,18 kDa phosphoprotein,p18,Cofilin,non-muscle isoform,CFL2,Cofilin-2,Cofilin,muscle isoform

      Size:
      • 20μL
      • 60μL
      • 120μL
      • 200μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H,M,R

      Applications: WB,IF,ELISA

      Lead Time: 7~10 daysWelcome to order from local distributors.

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      Overview

      Synonyms CFL1,CFL,Cofilin-1,18 kDa phosphoprotein,p18,Cofilin,non-muscle isoform,CFL2,Cofilin-2,Cofilin,muscle isoform
      Swissprot P23528,Q9Y281
      Source Rabbit
      Reactivity Human,Mouse,Rat
      Immunogen Synthesized peptide derived from the Internal region of human Cofilin
      Application WB,IF,ELISA
      Recommended dilution WB 1:500-1:2000, IF 1:200-1:1000, ELISA 1:40000
      Concentration 1mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Cofilin 1: Nucleus matrix. Cytoplasm, cytoskeleton. Cell projection, ruffle membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection, lamellipodium membrane; Peripheral membrane protein; Cytoplasmic side. Note: Colocalizes with the actin cytoskeleton in membrane ruffles and lamellipodia. Detected at the cleavage furrow and contractile ring during cytokinesis. Almost completely in nucleus in cells exposed to heat shock or 10% dimethyl sulfoxide. Cofilin 2: Nucleus matrix. Cytoplasm, cytoskeleton
      Tissue specificity Widely distributed in various tissues.
      Isotype IgG
      Purification Affinity purification
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.02% sodium azide,0.5% BSA and 50% glycerol pH 7.4.
      Background Controls reversibly actin polymerization and depolymerization in a pH-sensitive manner. It has the ability to bind G- and F-actin in a 1:1 ratio of cofilin to actin. It is the major component of intranuclear and cytoplasmic actin rods.

      Images

      Western Blot analysis of Jurkat cells using Cofilin Polyclonal Antibody at dilution of 1:1000.

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