Alternate Names	Vascular cell adhesion protein 1,Vcam1,V-CAM 1,VCAM-1,CD106
Swissprot	P29533
References	1. Barclay AN, et al. 1997. The Leukocyte Antigen FactsBook Academic Press. 2. Kinashi T, et al. 1995. J. Leukoc. Biol. 57:168. 3. Bevilacquea MP. 1993. Annu. Rev. Immunol. 11:767. 4. Koni PA, et al. 2001. J. Exp. Med. 193:741.

Product Details

Form	Liquid
Clone No.	M/K-2.7(See Other Available Formats)
Host	Rat
Isotype	Rat IgG1, κ
Isotype Control	Elab Fluor^® 488 Rat IgG1, κ Isotype Control[HRPN] [Product E-AB-F09823L]
Reactivity	Mouse
Application	FCM (See the Application Description)
Storage Buffer	Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Recommended Use	Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/10⁶ cells in 100 μL volume].
Shipping	Biological ice pack at 4℃
Stability & Storage	Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Conjugation	Elab Fluor^® 488
	Elab Fluor^® 488 is designed to be excited by the Blue laser (488 nm) and detected using an optical filter centered near 520 nm (e.g., a 525/40 nm bandpass filter).

How to select the appropriate detection channel through the spectrogram?

Background

CD106 is a 110 kD glycosylphosphatidylinositol (GPI)-linked transmembrane protein, also known as VCAM-1 and INCAM-110. It is constitutively expressed on bone marrow stromal cells, myeloid progenitors, splenic dendritic cells, activated endothelial cells, as well as some lymphocytes. CD106 expression can be upregulated on endothelial cells by inflammatory cytokines. CD106 is involved in adhesion and acts as a counter-receptor for VLA-4 (α4/β1 integrin) and LPAM-1 (α4/β7 integrin).

Protocols & Troubleshootings

Related Protocols	Staining Cell Surface Targets for Flow Cytometry
Troubleshooting	Troubleshooting for Flow Cytometry

Alternative Formats

Product Name	Sizes	Price
AF/LE Purified Anti-Mouse CD106 Antibody[M/K-2.7]	50μg, 500μg, 1mg	Check More
Purified Anti-Mouse CD106 Antibody[M/K-2.7]	25μg, 100μg	Check More
Biotin Anti-Mouse CD106 Antibody[M/K-2.7]	25μg, 100μg	Check More
FITC Anti-Mouse CD106 Antibody[M/K-2.7]	50Tests, 100Tests, 100Tests×2	Check More
PE Anti-Mouse CD106 Antibody[M/K-2.7]	50Tests, 100Tests, 100Tests×2	Check More
APC Anti-Mouse CD106 Antibody[M/K-2.7]	50Tests, 100Tests, 100Tests×2	Check More
PE/Cyanine5 Anti-Mouse CD106 Antibody[M/K-2.7]	50Tests, 100Tests, 100Tests×2	Check More
PE/Cyanine7 Anti-Mouse CD106 Antibody[M/K-2.7]	50Tests, 100Tests, 100Tests×2	Check More
PE/Cyanine5.5 Anti-Mouse CD106 Antibody[M/K-2.7]	50Tests, 100Tests, 100Tests×2	Check More
PerCP/Cyanine5.5 Anti-Mouse CD106 Antibody[M/K-2.7]	50Tests, 100Tests, 100Tests×2	Check More
Elab Fluor^® 488 Anti-Mouse CD106 Antibody[M/K-2.7]	50Tests, 100Tests, 100Tests×2	Check More
Elab Fluor^® 647 Anti-Mouse CD106 Antibody[M/K-2.7]	50Tests, 100Tests, 100Tests×2	Check More
PE/Elab Fluor^® 594 Anti-Mouse CD106 Antibody[M/K-2.7]	50Tests, 100Tests, 100Tests×2	Check More
FITC Anti-Mouse CD106 Antibody[M/K-2.7]	25μg, 100μg	Check More
PE Anti-Mouse CD106 Antibody[M/K-2.7]	25μg, 100μg	Check More
APC Anti-Mouse CD106 Antibody[M/K-2.7]	25μg, 100μg	Check More
PE/Cyanine5 Anti-Mouse CD106 Antibody[M/K-2.7]	25μg, 100μg	Check More
PE/Cyanine7 Anti-Mouse CD106 Antibody[M/K-2.7]	25μg, 100μg	Check More
PE/Cyanine5.5 Anti-Mouse CD106 Antibody[M/K-2.7]	25μg, 100μg	Check More
PerCP/Cyanine5.5 Anti-Mouse CD106 Antibody[M/K-2.7]	25μg, 100μg	Check More
Elab Fluor^® 647 Anti-Mouse CD106 Antibody[M/K-2.7]	25μg, 100μg	Check More
PE/Elab Fluor^® 594 Anti-Mouse CD106 Antibody[M/K-2.7]	25μg, 100μg	Check More

Citations

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