Alternate Names	Integrin beta-2,Itgb2,Cell surface adhesion glycoproteins LFA-1/CR3/p150+95 subunit beta,Complement receptor C3 subunit beta,CD18
Swissprot	P11835
References	1. Barclay AN, et al. 1997. The Leukocyte Antigen FactsBook Academic Press. 2. Anderson DC, et al. 1987. Annu. Rev. Med. 38:175. 3. Wilson RW, et al. 1993. J. Immunol. 151:1571.

Product Details

Form	Liquid
Clone No.	M18/2(See Other Available Formats)
Host	Rat
Isotype	Rat IgG2a, κ
Isotype Control	Elab Fluor^® 488 Rat IgG2a, κ Isotype Control[2A3] [Product E-AB-F09833L]
Reactivity	Mouse
Application	FCM (See the Application Description)
Storage Buffer	Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Recommended Use	Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/10⁶ cells in 100 μL volume].
Shipping	Biological ice pack at 4℃
Stability & Storage	Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Conjugation	Elab Fluor^® 488
	Elab Fluor^® 488 is designed to be excited by the Blue laser (488 nm) and detected using an optical filter centered near 520 nm (e.g., a 525/40 nm bandpass filter).

How to select the appropriate detection channel through the spectrogram?

Background

CD18 is a 95 kD protein, also known as integrin β2 subunit. It is expressed on all leukocytes. CD18, in association with integrin α chain CD11a, CD11b, and CD11c forms LFA-1, Mac-1, and αXβ2, respectively, and plays an important role in leukocytes adhesion. The CD18 integrin complexes bind ICAM-1 (CD54), ICAM-2 (CD102), ICAM-3 (CD50), iC3b, and fibrinogen.

Protocols & Troubleshootings

Related Protocols	Staining Cell Surface Targets for Flow Cytometry
Troubleshooting	Troubleshooting for Flow Cytometry

Alternative Formats

Product Name	Sizes	Price
AF/LE Purified Anti-Mouse CD18 Antibody[M18/2] E-AB-F11130	50μg, 500μg, 1mg	Check More
Purified Anti-Mouse CD18 Antibody[M18/2] E-AB-F1113A	25μg, 100μg	Check More
Biotin Anti-Mouse CD18 Antibody[M18/2] E-AB-F1113B	25μg, 100μg	Check More
FITC Anti-Mouse CD18 Antibody[M18/2] E-AB-F1113C	50Tests, 100Tests, 100Tests×2	Check More
PE Anti-Mouse CD18 Antibody[M18/2] E-AB-F1113D	50Tests, 100Tests, 100Tests×2	Check More
PE/Cyanine7 Anti-Mouse CD18 Antibody[M18/2] E-AB-F1113H	50Tests, 100Tests, 100Tests×2	Check More
Elab Fluor^® 488 Anti-Mouse CD18 Antibody[M18/2]	50Tests, 100Tests, 100Tests×2	Check More
FITC Anti-Mouse CD18 Antibody[M18/2] E-AB-F1113UC	25μg, 100μg	Check More
PE Anti-Mouse CD18 Antibody[M18/2] E-AB-F1113UD	25μg, 100μg	Check More
PE/Cyanine7 Anti-Mouse CD18 Antibody[M18/2] E-AB-F1113UH	25μg, 100μg	Check More

Citations

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