FGR Polyclonal Antibody

Uniprot: P09769
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
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    >
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-30892

      Synonyms:c fgr,c fgr protooncogene,c src 2 proto oncogene,c src2,Fgr,FGR,FLJ43153,Gardner Rasheed feline sarcoma viral (v fgr),Gardner Rasheed feline sarcoma viral (v fgr) oncogene homolog,Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog,MGC75096,p55 c fgr protein,P55 FGR,P55-FGR,p55c fgr,p58-Fgr,p58c fgr,p58c-Fgr,Proto oncogene c Fgr,Proto oncogene tyrosine protein kinase FGR,Proto-oncogene c-Fgr,SRC 2,SRC2,Tyrosine protein kinase Fgr,Tyrosine-protein kinase Fgr

      Size:
      • 20μL
      • 60μL
      • 120μL
      • 200μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H

      Applications: WB,IHC-p,ELISA

      Lead Time: 7~10 daysWelcome to order from local distributors.

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      Overview

      Synonyms c fgr,c fgr protooncogene,c src 2 proto oncogene,c src2,Fgr,FGR,FLJ43153,Gardner Rasheed feline sarcoma viral (v fgr),Gardner Rasheed feline sarcoma viral (v fgr) oncogene homolog,Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog,MGC75096,p55 c fgr protein,P55 FGR,P55-FGR,p55c fgr,p58-Fgr,p58c fgr,p58c-Fgr,Proto oncogene c Fgr,Proto oncogene tyrosine protein kinase FGR,Proto-oncogene c-Fgr,SRC 2,SRC2,Tyrosine protein kinase Fgr,Tyrosine-protein kinase Fgr
      Swissprot P09769
      Source Rabbit
      Reactivity Human
      Immunogen Synthesized peptide derived from human c-Fgr around the non-phosphorylation site of Y412.
      Application WB,IHC-p,ELISA
      Recommended dilution WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:40000
      Concentration 1mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Cell membrane. Cell membrane. Cell projection>ruffle membrane. Cytoplasm>cytosol. Cytoplasm>cytoskeleton. Mitochondrion inner membrane. Mitochondrion intermembrane space. Detected in mitochondrial intermembrane space and at inner membranes (By similarity). Colocalizes with actin fibers at membrane ruffles. Detected at plasma membrane lipid rafts.
      Tissue specificity Detected in neutrophils, monocytes and natural killer cells (at protein level). Detected in monocytes and large lymphocytes.
      Isotype IgG
      Purification Affinity purification
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.02% sodium azide,0.5% BSA and 50% glycerol pH 7.4.
      Background This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to plasma membrane ruffles, and functions as a negative regulator of cell migration and adhesion triggered by the beta-2 integrin signal transduction pathway. Infection with Epstein-Barr virus results in the overexpression of this gene. Multiple alternatively spliced variants, encoding the same protein, have been identified.

      Images

      Western Blot analysis of RAW264.7 cells with FGR Polyclonal Antibody

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