FITC Anti-Human/Monkey CD20 Antibody[2H7] (E-AB-F1212C)

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Cell Markers

Size	Price	Qty
100Tests	$ 120.00	- +
20Tests	$ 40.00	- +
100Tests×2	$ 192.00	- +

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Conjugation: FITC

Isotype	Mouse IgG2b, κ
Host	Mouse
Reactivity	Human, Rhesus, Cynomolgus
Applications	FCM
Clonality	Monoclonal
Isotype Control	FITC Mouse IgG2b, κ Isotype Control[MPC-11]
Abbre	CD20
Synonyms	B-lymphocyte surface antigen B1, Bp35, Leukocyte surface antigen Leu-16, MS4A1
Swissprot	P11836
Cellular Localization	Membrane
Concentration	5 μL/Test
Buffer	Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer.
Research Areas	Costimulatory Molecules, Immunology
Clone No.	2H7
Conjugation	FITC
Conjugation Information	FITC is designed to be excited by the Blue laser (488 nm) and detected using an optical filter centered near 530 nm (e.g., a 525/40 nm bandpass filter).
Spectrum
Storage	This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Shipping	Ice bag
background	CD20 is a 33-37 kD, four transmembrane spanning protein, also known as B1 and Bp35. CD20 is expressed on pre-B-cells, resting and activated B cells (not plasma cells), some follicular dendritic cells, and at low levels on a T cell subset. CD20 is heavily phosphorylated on activated B cells and malignant B cells. Homo-oligomeric complexes of CD20 are thought to form Ca2+ conductive ion channels in the plasma membrane of B cells. The CD20 molecule is involved in B-cell activation and is associated with various Src family kinases (Lyn, Lck, Fyn). It exists in a complex with MHC class I and II, CD53, CD81, and CD82.