GAS2 Polyclonal Antibody

Uniprot : O43903
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
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    >
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-14096

      Synonyms:GAS 2,GAS-2,Gas2,GAS2,Growth arrest specific 2,Growth arrest specific protein 2,Growth arrest-specific protein 2,MGC32610

      Size:
      • 20μL
      • 60μL
      • 120μL
      • 200μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H,M

      Applications: IHC,ELISA

      Lead Time: 7~10 daysWelcome to order from local distributors.

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      Overview

      Synonyms GAS 2,GAS-2,Gas2,GAS2,Growth arrest specific 2,Growth arrest specific protein 2,Growth arrest-specific protein 2,MGC32610
      Swissprot O43903
      Source Rabbit
      Reactivity Human,Mouse
      Immunogen Recombinant protein of human GAS2
      Application IHC(Detection kit: E-IR-R213),ELISA
      Recommended dilution IHC 1:25-1:100
      Concentration 0.3 mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Cytoplasm>cytoskeleton. Membrane. Component of the microfilament system. Colocalizes with actin fibers at the cell border and along the stress fibers in growth-arrested fibroblasts. Mainly membrane-associated. When hyperphosphorylated, accumulates at membrane ruffles.
      Tissue specificity Ubiquitously expressed with highest levels in liver, lung, and kidney. Not found in spleen.
      Isotype IgG
      Purification Affinity purification
      Conjugation Unconjugated
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
      Background The protein encoded by this gene is a caspase-3 substrate that plays a role in regulating microfilament and cell shape changes during apoptosis. It can also modulate cell susceptibility to p53-dependent apoptosis by inhibiting calpain activity. Multiple alternatively spliced variants, encoding the same protein, have been identified.

      Images

      Immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using GAS2 Polyclonal Antibody at dilution 1:30

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