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GFI1 Polyclonal Antibody

Cat:E-AB-17997
Manual MSDS

Price: $ 399

Price: $ 240

Price: $ 143

Price: $ 73

Size:
200μL 120μL 60μL 20μL
Quantity:
  • Host: Rabbit
  • Reactivity: Human; Mouse; Rat
  • Applications: IHC
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Product Details
Verified Samples Verified Samples in IHC:Human cervical cancer,Human colorectal cancer
Dilution

IHC 1:50-1:300

Western Blot Operation Guide
Clonality Polyclonal
Immunogen Synthetic peptide of human GFI1
Abbre GFI1
Synonyms GFI 1;GFI1;GFI1;Growth factor independence 1;Growth factor independent 1;Growth factor independent protein 1;SCN2;Zinc finger protein 163;Zinc finger protein Gfi 1;Zinc finger protein Gfi-1;Zinc finger protein Gfi1;ZNF 163;ZNF163
Swissprot
Cellular Localization Nucleus.
Concentration 1.62 mg/mL
Buffer PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Purification Method Antigen affinity purification
Research Areas Cancer; Epigenetics and Nuclear Signaling
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping Ice bag
background This gene encodes a nuclear zinc finger protein that functions as a transcriptional repressor. This protein plays a role in diverse developmental contexts, including hematopoiesis and oncogenesis. It functions as part of a complex along with other cofactors to control histone modifications that lead to silencing of the target gene promoters. Mutations in this gene cause autosomal dominant severe congenital neutropenia, and also dominant nonimmune chronic idiopathic neutropenia of adults, which are heterogeneous hematopoietic disorders that cause predispositions to leukemias and infections. Multiple alternatively spliced variants, encoding the same protein, have been identified for this gene.