GLUT-4 Polyclonal Antibody

Uniprot : P14672
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    <
    >
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-31558

      Synonyms:insulin-responsive,Glucose transporter GLUT 4,Glucose transporter type 4,Glucose transporter type 4 insulin responsive,GLUT 4,GLUT-4,GLUT4,GTR4,Insulin responsive glucose transporter type 4,kug,SLC 2A4,SLC2A4,solute carrier family 2 (facilitated glucose transporter) member 4,Solute carrier family 2 member 4,Solute carrier family 2,facilitated glucose transporter member 4

      Size:
      • 20 μL
      • 60 μL
      • 120 μL
      • 200 μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H,M,R

      Applications: WB,IHC-p,ELISA

      Lead Time: 2 daysWelcome to order from local distributors.

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      Overview

      Synonyms insulin-responsive,Glucose transporter GLUT 4,Glucose transporter type 4,Glucose transporter type 4 insulin responsive,GLUT 4,GLUT-4,GLUT4,GTR4,Insulin responsive glucose transporter type 4,kug,SLC 2A4,SLC2A4,solute carrier family 2 (facilitated glucose transporter) member 4,Solute carrier family 2 member 4,Solute carrier family 2,facilitated glucose transporter member 4
      Swissprot P14672
      Source Rabbit
      Reactivity Human,Mouse,Rat
      Immunogen Synthesized peptide derived from the Internal region of human Glut4.
      Application WB(Detection kit: E-IR-R304),IHC-p(Detection kit: E-IR-R213),ELISA
      Recommended dilution WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:40000
      Concentration 1mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Cell membrane. Endomembrane system. Cytoplasm, perinuclear region. Localizes primarily to the perinuclear region, undergoing continued recycling to the plasma membrane where it is rapidly reinternalized. The dileucine internalization motif is critical for intracellular sequestration.
      Tissue specificity Skeletal and cardiac muscles; brown and white fat.
      Isotype IgG
      Purification Affinity purification
      Conjugation Unconjugated
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
      Background This gene is a member of the solute carrier family 2 (facilitated glucose transporter) family and encodes a protein that functions as an insulin-regulated facilitative glucose transporter. In the absence of insulin, this integral membrane protein is sequestered within the cells of muscle and adipose tissue. Within minutes of insulin stimulation, the protein moves to the cell surface and begins to transport glucose across the cell membrane. Mutations in this gene have been associated with noninsulin-dependent diabetes mellitus (NIDDM).

      Images

      Western Blot analysis of HepG2 cells using GLUT-4 Polyclonal Antibody at dilution of 1:2000.

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