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Human IL-6(Interleukin 6) ELISA Kit

  • Cat.No.:E-EL-H0102

  • Reactivity: Human

To Purchase E-EL-H0102

Size:
  • 96T
  • 48T
  • 24T
  • 96T*5
  • 96T*10
Price: $495
Qty:

Product Details

Properties

Assay type Sandwich-ELISA
Format 96T/48T
Assay time 3.5h
Detection range 7.81-500 pg/mL
Sensitivity 4.69 pg/mL
Sample type &Sample volume serum, plasma and other biological fluids; 100μL
Specificity This kit recognizes Human IL-6 in samples. No significant cross-reactivity or interference between Human IL-6 and analogues was observed.
Reproducibility Both intra-CV and inter-CV are < 10%.
Application This ELISA kit applies to the in vitro quantitative determination of Human IL-6 concentrations in serum, plasma and other biological fluids.

Test Principle

This ELISA kit uses the Sandwich-ELISA principle. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to Human IL-6. Standards or samples are added to the micro ELISA plate wells and combined with the specific antibody. Then a biotinylated detection antibody specific for Human IL-6 and Avidin-Horseradish Peroxidase (HRP) conjugate are added successively to each micro plate well and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain Human IL-6, biotinylated detection antibody and Avidin-HRP conjugate will appear blue in color. The enzyme-substrate reaction is terminated by the addition of stop solution and the color turns yellow. The optical density (OD) is measured spectrophotometrically at a wavelength of 450 nm ± 2 nm. The OD value is proportional to the concentration of Human IL-6. You can calculate the concentration of Human IL-6 in the samples by comparing the OD of the samples to the standard curve.

Kit components & Storage

An unopened kit can be stored at 2-8℃ for 1 month. If the kit is not supposed to be used within 1 month, store the components separately according to the following conditions once the kit is received.
ItemSpecificationsStorage
Micro ELISA Plate(Dismountable) 96T: 8 wells ×12 strips
48T: 8 wells ×6 strips
-20℃, 6 months
Reference Standard 96T: 2 vials
48T: 1 vial
Concentrated Biotinylated Detection Ab (100×) 96T: 1 vial, 120 μL
48T: 1 vial, 60 μL
Concentrated HRP Conjugate (100×) 96T: 1 vial, 120 μL
48T: 1 vial, 60 μL
-20℃(Protect from light), 6 months
Reference Standard & Sample Diluent 1 vial, 20 mL 2-8°C, 6 months
Biotinylated Detection Ab Diluent 1 vial, 14 mL
HRP Conjugate Diluent 1 vial, 14 mL
Concentrated Wash Buffer (25×) 1 vial, 30 mL
Substrate Reagent 1 vial, 10 mL 2-8℃(Protect from light)
Stop Solution 1 vial, 10 mL 2-8°C
Plate Sealer 5 pieces
Manual 1 copy
Certificate of Analysis 1 copy

Technical Data

Precision

Intra-assay Precision (Precision within an assay): 3 samples with low, mid range and high level Human IL-6 were tested 20 times on one plate, respectively.
Inter-assay Precision (Precision between assays): 3 samples with low, mid range and high level Human IL-6 were tested on 3 different plates, 20 replicates in each plate.

  Intra-assay Precision Inter-assay Precision
Sample 1 2 3 1 2 3
n 20 20 20 20 20 20
Mean (pg/mL) 25.30 67.60 210.10 24.20 66.50 197.40
Standard deviation 1.70 2.80 7.80 1.60 3.40 6.70
CV (%) 6.72 4.14 3.71 6.61 5.11 3.39

Recovery

The recovery of Human IL-6 spiked at three different levels in samples throughout the range of the assay was evaluated in various matrices.

Sample Type Range (%) Average Recovery (%)
Serum(n=8) 97-110 102
EDTA plasma (n=8) 92-108 99
Cell culture media (n=8) 95-109 101

Linearity

Samples were spiked with high concentrations of Human IL-6 and diluted with Reference Standard & Sample Diluent to produce samples with values within the range of the assay.

Target Information

Database LinksSwissProt: P05231
SynonymsIL6, BSF2, HGF, HSF, IFNB2, CDF
Research AreaCancer,Immunology,Neuroscience

Assay Procedures

elisa assay procedure 1

1. Add 100μL standard or sample to the wells. Incubate for 90 min at 37°C

elisa assay procedure 2

2. Discard the liquid, immediately add 100μL Biotinylated Detection Ab working solution to each well. Incubate for 60 min at 37°C

elisa assay procedure 3

3. Aspirate and wash the plate for 3 times

elisa assay procedure 4

4. Add 100μL HRP conjugate working solution. Incubate for 30 min at 37°C. Aspirate and wash the plate for 5 times

elisa assay procedure 5

5. Add 90μL Substrate Reagent. Incubate for 15 min at 37°C

elisa assay procedure 6

6. Add 50μL Stop Solution

elisa assay procedure 7

7. Read the plate at 450nm immediately. Calculation of the results

Citations

From now on, if you have published a paper by using any of our products since 1/1/2019, fill out the “Elabscience Publication Reward Application Form”carefully and send it to orders@elabscience.com, we will get back to you with the reward after we confirm it ASAP!

View more details about our Publication Reward >>

  1. Hepatology (2020) IF: 14.679
    Increased Liver Localization of Lipopolysaccharides in Human and Experimental NAFLD

    DOI: 10.1002/hep.31056

    PMID: 31808577

    Sample: Serum
  2. Acs Nano (2017) IF: 13.942
    Overcoming The Heat Endurance Of Tumor Cells By Interfering The Anaerobic Glycolysis Metabolism For Improved Photothermal Therapy.

    DOI: 10.1021/acsnano.6b06658

    PMID: 28107631

    Sample: Cell culture supernatant
  3. ACS Applied Materials & Interfaces (2014) IF: 8.097
    Flexible Gold Electrode Array For Multiplexed Immunoelectrochemical Measurement Of Three Protein Biomarkers For Prostate Cancer.

    DOI: 10.1021/am505726b

    PMID: 25333408

  4. Carbohydrate Polymers (2020) IF: 7.182
    Dual functionalized chitosan based composite hydrogel for haemostatic efficacy and adhesive property

    DOI: 10.1016/j.carbpol.2020.116757

    PMID: 32829870

    Sample: Cell culture supernatant
  5. Chemosphere (2020) IF: 5.778
    PM2.5 organic extract mediates inflammation through the ERβ pathway to contribute to lung carcinogenesis in vitro and vivo

    DOI: 10.1016/j.chemosphere.2020.127867

    PMID: 32841872

    Sample: Cell culture supernatant
  6. Journal of Cellular Physiology (2020) IF: 5.546
    Cytokine physiognomies of MSCs from varied sources confirm the regenerative commitment post-coculture with activated neutrophils

    DOI: 10.1002/jcp.29713

    PMID: 32385929

    Sample: Cell culture supernatant
  7. Liver International (2020) IF: 5.175
    Fontan protein-losing enteropathy is associated with advanced liver disease and a proinflammatory intestinal and systemic state

    DOI: 10.1111/liv.14375

    PMID: 31912956

    Sample: Plasma
  8. Clinical Science (2020) IF: 5.223
    Effects of circulating extracellular microvesicles from spinal cord-injured adults on endothelial cell function

    DOI: 10.1042/CS20200047

    PMID: 32219341

    Sample: Cell culture supernatant
  9. Oxidative Medicine and Cellular Longevity (2019) IF: 5.076
    Resveratrol Inhibits MMP3 and MMP9 Expression and Secretion by Suppressing TLR4/NF- κ B/STAT3 Activation in Ox-LDL-Treated HUVECs

    DOI: 10.1155/2019/9013169

    PMID: 31583048

    Sample: Cell culture supernatant
  10. IF: 5.714
    Activation of NF-κB pathways mediating the inflammation and pulmonary diseases associated with atmospheric methylamine exposure
    Sample: Cell supernatant
  11. Environmental Pollution (2019) IF: 5.714
    Activation of NF-κB pathways mediating the inflammation and pulmonary diseases associated with atmospheric methylamine exposure

    DOI: 10.1016/j.envpol.2019.06.059

    PMID: 31252119

    Sample: Cell culture supernatant
  12. Osteoarthritis and cartilage (2018) IF: 5.454
    Associations between knee structural measures, circulating inflammatory factors and MMP13 in patients with knee osteoarthritis.

    DOI: 10.1016/j.joca.2018.05.003

    PMID: 29753949

    Sample: Serum
  13. Journal of Agricultural and Food Chemistry (2020) IF: 4.192
    Changes in Allergenicity of Ovalbumin in Vitro and in Vivo on Conjugation with Quercetin

    DOI: 10.1021/acs.jafc.0c00461

    PMID: 32182051

    Sample: Serum,Cell culture supernatant
  14. Frontiers in Pharmacology (2020) IF: 4.225
    Network Pharmacology-Based Strategy to Investigate the Pharmacologic Mechanisms of Atractylodes macrocephala Koidz. for the Treatment of Chronic Gastritis

    DOI: 10.3389/fphar.2019.01629

    PMID: 32063848

    Sample: Cell culture supernatant
  15. Biomedicine & Pharmacotherapy (2020) IF: 4.545
    LncRNA SNHG5 regulates cell apoptosis and inflammation by miR-132/PTEN axis in COPD

    DOI: 10.1016/j.biopha.2020.110016

    PMID: 32145584

    Sample: Cell culture supernatant
  16. Biomedicine & Pharmacotherapy (2020) IF: 4.545
    Long non-coding RNA NNT-AS1 regulates proliferation, apoptosis, inflammation and airway remodeling of chronic obstructive pulmonary disease via targeting miR-582-5p/FBXO11 axis

    DOI: 10.1016/j.biopha.2020.110326

    PMID: 99999999

    Sample: Cell culture supernatant
  17. European Journal of Internal Medicine (2020) IF: 4.329
    Treating periodontal disease in patients with myocardial infarction: A randomized clinical trial

    DOI: 10.1016/j.ejim.2019.08.012

    PMID: 31810741

    Sample: Serum
  18. Clinical & Experimental Allergy (2020) IF: 4.217
    Relationship between immune parameters during a severe exacerbation in allergic asthmatic children and asthma outcomes in the following year

    DOI: 10.1111/cea.13570

    PMID: 31955476

    Sample: Plasma
  19. Diabetes research and clinical practice (2019) IF: 4.234
    Effect of Ramadan diurnal fasting on visceral adiposity and serum adipokines in overweight and obese individuals

    DOI: 10.1016/j.diabres.2019.05.023

    PMID: 31150725

    Sample: Serum
  20. Cells (2018) IF: 4.829
    Mesenchymal Stem Cells (MSCs) Coculture Protects [Ca2+] i Orchestrated Oxidant Mediated Damage in Differentiated Neurons In Vitro

    DOI: 10.3390/cells7120250

    PMID: 30563298

    Sample: Cell culture supernatant
  21. Scientific Reports (2016) IF: 4.259
    TLR3-/4-Priming Differentially Promotes Ca2+Signaling And Cytokine Expression And Ca2+-Dependently Augments Cytokine Release In hMSCs.

    DOI: 10.1038/srep23103

    PMID: 26980664

    Sample: Cell culture supernatant
  22. Journal of Cellular and Molecular Medicine (2017) IF: 4.499
    The Classic Signalling And Trans-signalling Of Interleukin-6 Are Both Injurious In Podocyte Under High Glucose Exposure.

    DOI: 10.1111/jcmm.13314

    PMID: 28881473

    Sample: Serum
  23. Bioconjugate Chemistry (2016) IF: 4.818
    Multifunctional Dextran Sulfate-Coated Reconstituted High Density Lipoproteins Target Macrophages And Promote Beneficial Antiatherosclerotic Mechanisms.

    DOI: 10.1021/acs.bioconjchem.6b00600

    PMID: 28004910

    Sample: Cell culture supernatant
  24. Scientific reports (2020) IF: 3.998
    Early modulation of macrophage ROS-PPARγ-NF-κB signalling by sonodynamic therapy attenuates neointimal hyperplasia in rabbits

    DOI: 10.1038/s41598-020-68543-9

    PMID: 32669704

    Sample: Cell culture supernatant
  25. Mediators of inflammation (2020) IF: 3.758
    IL-37 Exerts Anti-Inflammatory Effects in Fetal Membranes of Spontaneous Preterm Birth via the NF- κ B and IL-6/STAT3 Signaling Pathway

    DOI: 10.1155/2020/1069563

    PMID: 32733162

    Sample: Cell culture supernatant
  26. International Immunopharmacology (2020) IF: 3.943
    IL-38 alleviates the inflammatory response and the degeneration of nucleus pulposus cells via inhibition of the NF-κB signaling pathway in vitro

    DOI: 10.1016/j.intimp.2020.106592

    PMID: 32502922

    Sample: Cell culture supernatant
  27. Mediators of Inflammation (2020) IF: 3.758
    Diagnostic and Prognostic Value of IL-6 and sTREM-1 in SIRS and Sepsis in Children

    DOI: 10.1155/2020/8201585

    PMID: 32655314

    Sample: Serum
  28. European review for medical and pharmacological sciences (2020) IF: 3.024
    miR-942-5p alleviates septic acute kidney injury by targeting FOXO3

    DOI: 10.26355/eurrev_202006_21521

    PMID: 32572890

    Sample: Cell culture supernatant
  29. Inflammopharmacology (2020) IF: 3.238
    Tocilizumab attenuates acute lung and kidney injuries and improves survival in a rat model of sepsis via down-regulation of NF-κB/JNK: a possible role of P-glycoprotein

    DOI: 10.1007/s10787-019-00628-y

    PMID: 31440860

    Sample: Serum
  30. Investigative ophthalmology & visual science (2020) IF: 3.47
    Perillaldehyde Ameliorates Aspergillus fumigatus Keratitis by Activating the Nrf2/HO-1 Signaling Pathway and Inhibiting Dectin-1-Mediated Inflammation

    DOI: 10.1167/iovs.61.6.51

    PMID: 32579678

    Sample: Cell lysate,Cell culture medium
  31. Schizophrenia Research (2020) IF: 3.759
    Chronic fatigue and fibromyalgia symptoms are key components of deficit schizophrenia and are strongly associated with activated immune-inflammatory pathways

    DOI: 10.1016/j.schres.2020.05.003

    PMID: 32467068

    Sample: Serum
  32. Fish & Shellfish Immunology (2019) IF: 3.298
    The first cloned echinoderm tumor necrosis factor receptor from Holothuria leucospilota: Molecular characterization and functional analysis

    DOI: 10.1016/j.fsi.2019.08.008

    PMID: 31394160

    Sample: Cell culture supernatant
  33. European review for medical and pharmacological sciences (2019) IF: 3.024
    Plasma concentration of ZCCHC14 contributes to prognostic efficacy in intracerebral hemorrhage patients

    DOI: 10.26355/eurrev_201910_19167

    PMID: 31646585

    Sample: Plasma
  34. Phytomedicine (2018) IF: 3.61
    Ethanolic extract of Kaempferia parviflora interrupts the mechanisms-associated rheumatoid arthritis in SW982 culture model via p38/STAT1 and STAT3 pathways

    DOI: 10.1016/j.phymed.2018.11.015

    PMID: 31005814

    Sample: Cell culture supernatant
  35. Life sciences (2019) IF: 3.234
    LncRNA PMS2L2 protects ATDC5 chondrocytes against lipopolysaccharide-induced inflammatory injury by sponging miR-203

    DOI: 10.1016/j.lfs.2018.12.020

    PMID: 30550887

    Sample: Cell culture supernatant
  36. Molecular immunology (2019) IF: 3.188
    IL-16 regulates macrophage polarization as a target gene of miR-145-3p

    DOI: 10.1016/j.molimm.2018.12.027

    PMID: 30634164

    Sample: Cell lysate
  37. Applied Physiology, Nutrition, and Metabolism (2018) IF: 3.455
    Acute long-distance trail running increases Serum IL-6, IL-15, and Hsp72 levels

    DOI: 10.1139/apnm-2018-0520

    PMID: 30365907

    Sample: Serum
  38. Biomedicine & Pharmacotherapy (2019) IF: 3.457
    Sapylin (OK-432) alters inflammation and angiogenesis in vivo and vitro

    DOI: 10.1016/j.biopha.2019.108706

    PMID: 30844656

    Sample: Wound drainage fluid
  39. Biomedicine & Pharmacotherapy (2018) IF: 3.457
    Biochemical investigation of gender-specific association between insulin resistance and inflammatory biomarkers in types 2 diabetic patients.

    DOI: 10.1016/j.biopha.2018.06.044

    PMID: 29966972

    Sample: Serum
  40. Journal of molecular endocrinology (2018) IF: 3.297
    ADSC-conditioned media elicit an ex vivo anti-inflammatory macrophage response.

    DOI: 10.1530/JME-18-0078

    PMID: 30038054

    Sample: Serum, Cell culture medium
  41. IUBMB Life (2016) IF: 3.141
    TSG Attenuates LPC-Induced Endothelial Cells Inflammatory Damage Through Notch Signaling Inhibition.

    DOI: 10.1002/iub.1458

    PMID: 26662286

    Sample: Cell culture supernatant
  42. Toxicology Letters (2017) IF: 3.858
    MicroRNA-218 Acts By Repressing TNFR1-Mediated Activation Of NF-κB, Which Is Involved In MUC5AC Hyper-Production And Inflammation In Smoking-Induced Bronchiolitis Of COPD.

    DOI: 10.1016/j.toxlet.2017.08.079

    PMID: 28864214

    Sample: Serum,Cell culture supernatant
  43. Apoptosis (2015) IF: 3.833
    In Vitro Antiproliferative, Pro-Apoptotic, Antimetastatic And Anti-Inflammatory Potential Of 2, 4-Diacteylphloroglucinol (DAPG) By Pseudomonas Aeruginosa Strain FP10.

    DOI: 10.1007/s10495-015-1162-9

    PMID: 26283170

    Sample: Cell culture supernatant
  44. Plos Neglected Tropical Diseases (2016) IF: 3.834
    Clonorchis Sinensis Co-Infection Could Affect The Disease State And Treatment Response Of Hbv Patients.

    DOI: 10.1371/journal.pntd.0004806

    PMID: 27348302

    Sample: Serum,Cell culture supernatant
  45. Food & Function (2016) IF: 3.247
    Antidiabetic (Type 2) Effects Of Lactobacillus G15 And Q14 In Rats Through Regulation Of Intestinal Permeability And Microbiota.

    DOI: 10.1039/c6fo00831c

    PMID: 27713957

    Sample: Plasma,Serum
  46. World Journal of Gastroenterology (2016) IF: 3.365
    Inhibitory Effect Of miR-125b On Hepatitis C Virus Core Protein-Induced TLR2/MyD88 Signaling In THP-1 Macrophages.

    DOI: 10.3748/wjg.v22.i17.4354

    PMID: 27158204

    Sample: Cell culture supernatant
  47. Cornea (2020) IF: 2.215
    Galectin-3, IL-1A, IL-6, and EGF Levels in Corneal Epithelium of Patients With Recurrent Corneal Erosion Syndrome

    DOI: 10.1097/ICO.0000000000002422

    PMID: 32732704

    Sample: Tissue homogenate
  48. Sleep and Breathing (2020) IF: 2.162
    Intermittent hypoxia induces tumor immune escape in murine S180 solid tumors via the upregulation of TGF-β 1 in mice

    DOI: 10.1007/s11325-020-02166-2

    PMID: 32840731

    Sample: Tissue homogenate
  49. Human & Experimental Toxicology (2020) IF: 2.067
    Investigation of DNA damage, oxidative stress, and inflammation in synthetic cannabinoid users

    DOI: 10.1177/0960327120930057

    PMID: 32508150

    Sample: Plasma
  50. Autoimmunity (2020) IF: 2.125
    Auto-reactivity against gut bacterial peptides in patients with late-onset diabetes

    DOI: 10.1080/08916934.2020.1818232

    PMID: 32924613

    Sample: Serum
  51. Archives of Physiology and Biochemistry (2020) IF: 2.575
    XIST silencing alleviated inflammation and mesangial cells proliferation in diabetic nephropathy by sponging miR-485

    DOI: 10.1080/13813455.2020.1789880

    PMID: 32669002

    Sample: Serum
  52. Journal of Zhejiang University. Science. B (2020) IF: 2.082
    Clinical characteristics of 34 COVID-19 patients admitted to intensive care unit in Hangzhou, China

    DOI: 10.1631/jzus.B2000174

    PMID: 32425003

    Sample: Serum,Plasma
  53. Immunopharmacology and Immunotoxicology (2020) IF: 2.352
    A case of asthma with Beh?et's disease: successful treatment with omalizumab and its effects on recurrent aphthous lesions

    DOI: 10.1080/08923973.2020.1789656

    PMID: 32605504

    Sample: Serum
  54. Biological Trace Element Research (2019) IF: 2.639
    Study of Metal-Metal Interactions and Their Biomarkers Using an Intestinal Human Cell Line

    DOI: 10.1007/s12011-019-01831-2

    PMID: 31473895

    Sample: Cell lysate
  55. Biochemical and Biophysical Research Communications (2020) IF: 2.985
    Long non-coding RNA MEG3 regulates CSE-induced apoptosis and inflammation via regulating miR-218 in 16HBE cells

    DOI: 10.1016/j.bbrc.2019.10.135

    PMID: 31668807

    Sample: Cell culture supernatant
  56. Innate Immunity (2020) IF: 2.298
    Functional characterisation of Holothuria leucospilota Fas-associated death domain in the innate immune-related signalling pathways

    DOI: 10.1177/1753425919877680

    PMID: 31550955

    Sample: Cell culture supernatant
  57. Poultry Science (2020) IF: 2.659
    The effect of different dietary ratios of arginine, methionine, and lysine on the performance, carcass traits, and immune status of turkeys

    DOI: 10.1016/j.psj.2019.10.008

    PMID: 32036960

    Sample: Plasma
  58. Hormone and Metabolic Research (2019) IF: 2.562
    Treatment with Metformin and Combination of Metformin Plus Pioglitazone on Serum Levels of IL-6 and IL-8 in Polycystic Ovary Syndrome: A Randomized Clinical Trial

    DOI: 10.1055/a-1018-9606

    PMID: 31683341

    Sample: Serum
  59. Microbial pathogenesis (2019) IF: 2.914
    Isolation, characterization and analysis of pro-inflammatory potential of Klebsiella pneumoniae outer membrane vesicles

    DOI: 10.1016/j.micpath.2019.103719

    PMID: 31493501

    Sample: Cell culture supernatant
  60. Acta tropica (2019) IF: 2.509
    Assessment of chemokine and cytokine signatures in patients with dengue infection: A hospital-based study in Kolkata, India

    DOI: 10.1016/j.actatropica.2018.10.017

    PMID: 30395811

    Sample: Serum
  61. Biochemical and biophysical research communications (2019) IF: 2.559
    Exosomes Derived From Human Umbilical Cord Mesenchymal Stem Cells Alleviate Acute Liver Failure by Reducing the Activity of the NLRP3 Inflammasome in Macrophages

    DOI: 10.1016/j.bbrc.2018.11.189

    PMID: 30528233

    Sample: Serum
  62. Journal of Oral Pathology & Medicine (2019) IF: 2.237
    Elevated leptin levels in temporomandibular joint osteoarthritis promote proinflammatory cytokine IL-6 expression in synovial fibroblasts

    DOI: 10.1111/jop.12819

    PMID: 30597628

    Sample: Cell culture supernatant
  63. Biomedicine & Pharmacotherapy (2018) IF: 2.759
    Oleanolic acid protects against pathogenesis of atherosclerosis, possibly via FXR-mediated angiotensin (Ang)-(1-7) upregulation.

    DOI: 10.1016/j.biopha.2017.11.151

    PMID: 29793333

    Sample: Cell culture supernatant,Serum
  64. International Journal of Molecular Medicine (2017) IF: 2.341
    Particulate Matter 2.5 Regulates Lipid Synthesis And Inflammatory Cytokine Production In Human SZ95 Sebocytes.

    DOI: 10.3892/ijmm.2017.3109

    PMID: 28849137

    Sample: Cell culture supernatant
  65. Plos One (2017) IF: 2.806
    Depot-Specific Inflammation With Decreased Expression Of ATM2 In White Adipose Tissues Induced By High-Margarine/Lard Intake.

    DOI: 10.1371/journal.pone.0188007

    PMID: 29141038

    Sample: Cell culture supernatant
  66. Plos One (2017) IF: 2.806
    High Anti-Human Cytomegalovirus Antibody Levels Are Associated With The Progression Of Essential Hypertension And Target Organ Damage In Han Chinese Population.

    DOI: 10.1371/journal.pone.0181440

    PMID: 28837559

    Sample: Serum
  67. Cardiovascular Pathology (2017) IF: 2.359
    C Reactive Protein And Enzymatically Modified LDL Cooperatively Promote Dendritic Cell-Mediated T Cell Activation.

    DOI: 10.1016/j.carpath.2017.03.009

    PMID: 28433861

    Sample: Cell culture supernatant
  68. Molecules (2015) IF: 2.861
    Mitochondrion-Targeted Peptide SS-31 Inhibited Oxidized Low-Density Lipoproteins-Induced Foam Cell Formation Through Both ROS Scavenging And Inhibition Of Cholesterol Influx In Raw264.7 Cells.

    DOI: 10.3390/molecules201219764

    PMID: 26633327

    Sample: Cell lysate
  69. Plos One (2013) IF: 2.806
    Oxidative Burst Of Circulating Neutrophils Following Traumatic Brain Injury In Human.

    DOI: 10.1371/journal.pone.0068963

    PMID: 23894384

    Sample: Plasma
  70. Archives of Oral Biology (2020) IF: 1.931
    Nec-1 attenuates inflammation and cytotoxicity induced by high glucose on THP-1 derived macrophages through RIP1

    DOI: 10.1016/j.archoralbio.2020.104858

    PMID: 32805637

    Sample: Cell culture supernatant
  71. Phlebology (2020) IF: 1.914
    Study of association of varicose veins and inflammation by inflammatory markers

    DOI: 10.1177/0268355520932410

    PMID: 32529904

    Sample: Plasma
  72. Lung (2020) IF: 1.817
    Are Serum Interleukin 6 and Surfactant Protein D Levels Associated with the Clinical Course of COVID-19?

    DOI: 10.1007/s00408-020-00393-8

    PMID: 32918573

    Sample: Plasma
  73. Experimental and Therapeutic Medicine (2020) IF: 1.785
    Curcumin affects ox-LDL-induced IL-6, TNF-α, MCP-1 secretion and cholesterol efflux in THP-1 cells by suppressing the TLR4/NF-κB/miR-3a signaling pathway

    DOI: 10.3892/etm.2020.8915

    PMID: 99999999

    Sample: Cell culture supernatant
  74. Medical Science Monitor (2020) IF: 1.918
    Avicularin Reduces the Expression of Mediators of Inflammation and Oxidative Stress in Bradykinin-Treated MG-63 Human Osteoblastic Osteosarcoma Cells

    DOI: 10.12659/MSM.921957

    PMID: 32463805

    Sample: Cell culture supernatant
  75. Experimental and Therapeutic Medicine (2020) IF: 1.785
    Systematically transplanted human gingiva-derived mesenchymal stem cells regulate lipid metabolism and inflammation in hyperlipidemic mice with periodontitis

    DOI: 10.3892/etm.2019.8256

    PMID: 31885706

    Sample: Serum
  76. Experimental and Therapeutic Medicine (2020) IF: 1.785
    Changes in expression of serum chemokine CXCL13 and IL-6 after hip replacement, and the relationship with lower limb vein thrombus

    DOI: 10.3892/etm.2019.8365

    PMID: 32104273

    Sample: Serum
  77. ANZ Journal of Surgery (2020) IF: 1.355
    Effect of laparoscopic sleeve gastrectomy on renal function in obese patients

    DOI: 10.1111/ans.15767

    PMID: 32115876

    Sample: Serum,Urine
  78. medicine (2019) IF: 1.552
    A case-control study on the relationship between miR-As single nucleotide polymorphisms and sepsis risk

    DOI: 10.1097/MD.0000000000016744

    PMID: 31415369

    Sample: Serum
  79. Journal of Clinical Neuroscience (2019) IF: 1.76
    Sex difference in IL-6 modulation of cognition among Chinese individuals with major depressive disorder

    DOI: 10.1016/j.jocn.2019.10.002

    PMID: 31629608

    Sample: Serum
  80. Molecular medicine reports (2019) IF: 1.922
    Chrysin protects human osteoarthritis chondrocytes by inhibiting inflammatory mediator expression via HMGB1 suppression

    DOI: 10.3892/mmr.2018.9724

    PMID: 30535473

    Sample: Cell culture medium
  81. Acta Odontologica Scandinavica (2019) IF: 1.522
    Leptin induces IL-6 and IL-8 expression through leptin receptor Ob-Rb in human dental pulp fibroblasts

    DOI: 10.1080/00016357.2018.1536280

    PMID: 30600742

    Sample: Cell culture supernatant
  82. Journal of Burn Care & Research (2019) IF: 1.923
    Mitochondrial DNA-Induced Inflammatory Responses and Lung Injury in Thermal Injury Murine Model: Protective Effect of Cyclosporine-A

    DOI: 10.1093/jbcr/irz029

    PMID: 30926991

    Sample: Serum
  83. Genetic testing and molecular biomarkers (2019) IF: 1.181
    Association of PAR-2 gene polymorphisms with the inflammatory response and susceptibility to knee osteoarthritis in the Chinese Han population

    DOI: 10.1089/gtmb.2018.0219

    PMID: 30688539

    Sample: Synovia
  84. Experimental and therapeutic medicine (2018) IF: 1.41
    Anti-inflammatory Effect of Resolvin D1 on LPS-treated MG-63 Cells

    DOI: 10.3892/etm.2018.6721

    PMID: 30402165

    Sample: Serum
  85. Experimental and Therapeutic Medicine (2019) IF: 1.41
    Effects of propofol combined with remifentanil anesthesia on the NO, endothelin and inflammatory cytokines in the plasma of patients with liver cirrhosis during the perioperative period

    DOI: 10.3892/etm.2019.7367

    PMID: 30988754

    Sample: Plasma
  86. Molecular Medicine Reports (2017) IF: 1.692
    Tetrahydroxy Stilbene Glucoside Ameliorates H2O2-Induced Human Brain Microvascular Endothelial Cell Dysfunction In Vitro By Inhibiting Oxidative Stress And Inflammatory Responses.

    DOI: 10.3892/mmr.2017.7225

    PMID: 28849141

    Sample: Cell culture supernatant
  87. Experimental and Therapeutic Medicine (2018) IF: 1.261
    Role Of miR-589-3p In Human Lumbar Disc Degeneration And Its Potential Mechanism.

    DOI: 10.3892/etm.2017.5593

    PMID: 29434746

    Sample: Cell culture supernatant
  88. Experimental and Therapeutic Medicine (2017) IF: 1.261
    Inhibition Of miR27a Suppresses The Inflammatory Response Via The p38/MAPK Pathway In Intervertebral Disc Cells.

    DOI: 10.3892/etm.2017.5053

    PMID: 29067127

    Sample: Cell culture supernatant
  89. American Journal of The Medical Sciences (2015) IF: 1.847
    Plasma Levels Of C1q/TNF-Related Protein 1 And Interleukin 6 In Patients With Acute Coronary Syndrome Or Stable Angina Pectoris.

    DOI: 10.1097/MAJ.9999999900000378

    PMID: 25635749

    Sample: Plasma
  90. The Journal of Maternal-Fetal & Neonatal Medicine (2020)
    Maternal omega-3 polyunsaturated fatty acids supplementation in pregnancy decreases MMP-1 levels in breastmilk: a cross-sectional study

    DOI: 10.1080/14767058.2020.1814241

    PMID: 32962453

    Sample: Milk
  91. Systematic Reviews in Pharmacy (2020)
    Atorvastatin Reload Down Regulates TLR-2 Expression and Reduces the Acute Inflammatory Response in Patients Undergoing Percutaneous Coronary Intervention

    DOI: 10.5530/srp.2020.2.52

    PMID: 99999999

    Sample: Serum
  92. JMSCR (2018)
    Evaluation of Cytokines Response in Plasmodium falciparum Infection among Adolescents in Port Harcourt, Nigeria

    DOI: 10.18535/jmscr/v6i9.54

    PMID: 99999999

    Sample: Plasma
  93. Indian Journal of Public Health Research & Development (2019)
    Association of Interleukin-6 Level with Some Clinical Parameters in Iraqi Juvenile Idiopathic Arthritis Patients

    DOI: 10.5958/0976-5506.2019.03164.4

    PMID: 99999999

    Sample: Serum
  94. Plant Archives (2020)
    STUDY OF SOME IMMUNOLOGICAL PARAMETERS FOR EXPOSURE TO PARTICULATE MATTER IN THE POPULATION OF BAGHDAD

    PMID: 99999999

    Sample: Serum
  95. International Journal of Biological and Chemical Sciences (2020)
    Level of VEGF-A and interleukin 6 in lacrimal fluid of patients with diabetic retinopathy

    DOI: 10.4314/ijbcs.v14i3.2

    PMID: 99999999

    Sample: Tears
  96. Indian Journal of Public Health Research & Development (2020)
    Correlation of Interleukin-6 with Serum Estradiol Mean Levels in Menopause Women at Rsup H Adam Malik Medan

    DOI: 10.37506/v11/i1/2020/ijphrd/194029

    PMID: 99999999

    Sample: Serum
  97. Preprint (2020)
    Increased interleukin-6 levels in neuron-derived plasma small extracellular vesicles in patients with aneurysmal subarachnoid hemorrhage

    DOI: 10.21203/rs.3.rs-15513/v1

    PMID: 99999999

    Sample: Plasma
  98. Preprint (2020)
    Thymosin β10 promotes tumor-associated macrophages M2 conversion and proliferation via the PI3K/Akt pathway in lung adenocarcinoma

    DOI: 10.21203/rs.3.rs-34263/v1

    PMID: 99999999

    Sample: Cell culture supernatant
  99. Open Journal of Ophthalmology (2020)
    Relationship between Angiogenic and Inflammatory Biomarkers and Diabetic Retinopathy

    DOI: 10.4236/ojoph.2020.101006

    PMID: 99999999

    Sample: Serum
  100. The Journal of Immunology (2020)
    CALML6 Controls TAK1 Ubiquitination and Confers Protection against Acute Inflammation

    DOI: 10.4049/jimmunol.1901042

    PMID: 32303555

    Sample: Cell culture supernatant
  101. Medico Legal Update (2020)
    Relation of Epstein Barr virus with Interleukin-6 Level among Women with Breast Cancer in Ramadi City

    DOI: 10.37506/v20/i1/2020/mlu/194497

    PMID: 99999999

    Sample: Plasma
  102. The Medical journal of Malaysia (2019)
    Association of -174 G>C interleukin-6 gene polymorphism with interleukin-6 and c-reactive protein levels and obesity: A case-control study among people/residents of Western Indonesia

    PMID: 31649216

    Sample: Plasma
  103. Revista da Associa??o Médica Brasileira (2019)
    TLR7 mediates increased vulnerability to ischemic acute kidney injury in diabetes

    DOI: 10.1590/1806-9282.65.8.1067

    PMID: 31531603

    Sample: Cell culture supernatant
  104. IOSR Journal of Dental and Medical Sciences (2016)
    Evaluation of IL-6 and TGF- β1level in serum and saliva of patients with systemic sclerosis

    DOI: 10.9790/0853-1509038892

    PMID: 99999999

    Sample: Serum,Saliva
  105. The Annals of thoracic surgery (2019)
    Impact of an Early Oral Feeding Protocol on Inflammatory Cytokine Changes After Esophagectomy

    DOI: 10.1016/j.athoracsur.2018.09.048

    PMID: 30403976

    Sample: Serum
  106. researchgate (2018)
    The Effect of Macrophage Dose To Secretion Interleukin 6 (IL-6) On Model of Tuberculosis Granuloma In Vitro

    DOI: 10.5220/0007541803060311

    PMID: 99999999

    Sample: Cell culture supernatant
  107. Journal of Physics: Conference Series (2019)
    Diabetes dance of persadia 1 effect on blood IL-6 level

    DOI: 10.1088/1742-6596/1146/1/012014

    PMID: 99999999

    Sample: Serum
  108. Modern Research in Inflammation (2019)
    Estimation of Cytokines Involved in Acute-Phase Wound Infection with Reference to Residence Time of Patients in Hospitals

    DOI: 10.4236/mri.2019.81001

    PMID: 99999999

    Sample: Serum
  109. Medical science monitor: international medical journal of experimental and clinical research (2018)
    Sinomenine Regulates Inflammatory Response and Oxidative Stress via Nuclear Factor kappa B (NF-kB) and NF-E2-Related Factor 2 (Nrf2) Signaling Pathways in Ankle Fractures in Children

    DOI: 10.12659/MSM.910740

    PMID: 30237391

    Sample: Serum
  110. University of Sulaimani (2018)
    EFFECTS OF GINKGO BILOBA EXTRACT (EGb761) AS ADDON WITH METFORMIN IN THE TREATMENT OF PATIENTS

    PMID: 99999999

    Sample: Serum
  111. Medical Science Monitor: International Medical Journal of Experimental And Clinical Research (2018) IF: /
    Propofol Promotes Ankle Fracture Healing in Children by Inhibiting Inflammatory Response.

    DOI: 10.12659/MSM.908592

    PMID: 29940605

    Sample: Serum
  112. Pediatric Allergy (2018) IF: 0.533
    High-Mobility Group Protein Box 1 is Upregulated in Children with Henoch-Schonlein Purpura.

    DOI: 10.1089/ped.2018.0872

    Sample: Serum
  113. Journal of Huazhong University of Science and Technology-Medical Sciences (2017) IF: 0.964
    Applied Value Of Monitoring Serum Hepcidin In Differential Diagnosis Of Infection Versus Tumor Fevers.

    DOI: 10.1007/s11596-017-1724-x

    PMID: 28397053

    Sample: Plasma
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