IGF2BP3 Polyclonal Antibody

Uniprot : O00425
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    <
    >
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-14148

      Synonyms:Cancer/testis antigen 98,CT98,DKFZp686F1078,hKOC,IF2B3,IGF II mRNA binding protein 3,IGF-II mRNA-binding protein 3,IGF2 mRNA binding protein 3,IGF2 mRNA-binding protein 3,IGF2BP3,IMP 3,IMP-3,Insulin like growth factor 2 mRNA binding protein 3,Insulin-like growth factor 2 mRNA-binding protein 3,KH domain containing protein overexpressed in cancer,KH domain-containing protein overexpressed in cancer,KOC 1,KOC1,VICKZ 3,VICKZ family member 3,VICKZ3

      Size:
      • 20μL
      • 60μL
      • 120μL
      • 200μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H,M

      Applications: WB,ELISA

      Lead Time: 7~10 daysWelcome to order from local distributors.

      Add to cart Compare Bulk request Manual

      Overview

      Synonyms Cancer/testis antigen 98,CT98,DKFZp686F1078,hKOC,IF2B3,IGF II mRNA binding protein 3,IGF-II mRNA-binding protein 3,IGF2 mRNA binding protein 3,IGF2 mRNA-binding protein 3,IGF2BP3,IMP 3,IMP-3,Insulin like growth factor 2 mRNA binding protein 3,Insulin-like growth factor 2 mRNA-binding protein 3,KH domain containing protein overexpressed in cancer,KH domain-containing protein overexpressed in cancer,KOC 1,KOC1,VICKZ 3,VICKZ family member 3,VICKZ3
      Swissprot O00425
      Source Rabbit
      Reactivity Human,Mouse
      Immunogen Recombinant protein of human IGF2BP3
      Application WB(Detection kit: E-IR-R304),ELISA
      Recommended dilution WB 1:500-1:2000
      Concentration 0.1 mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Nucleus. Cytoplasm. Found in lamellipodia of the leading edge, in the perinuclear region, and beneath the plasma membrane. The subcytoplasmic localization is cell specific and regulated by cell contact and growth. Localized at the connecting piece and the tail of the spermatozoa. Colocalized with CD44 mRNA in RNP granules.
      Tissue specificity Expressed in fetal liver, fetal lung, fetal kidney, fetal thymus, fetal placenta, fetal follicles of ovary and gonocytes of testis, growing oocytes, spermatogonia and semen (at protein level). Expressed in cervix adenocarcinoma, in testicular, pancreatic and renal-cell carcinomas (at protein level). Expressed ubiquitously during fetal development at 8 and 14 weeks of gestation. Expressed in ovary, testis, brain, placenta, pancreatic cancer tissues and pancreatic cancer cell lines.
      Isotype IgG
      Purification Affinity purification
      Conjugation Unconjugated
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.05% sodium azide and 50% glycerol, PH7.4
      Background The protein encoded by this gene is primarily found in the nucleolus, where it can bind to the 5' UTR of the insulin-like growth factor II leader 3 mRNA and may repress translation of insulin-like growth factor II during late development. The encoded protein contains several KH domains, which are important in RNA binding and are known to be involved in RNA synthesis and metabolism. A pseudogene exists on chromosome 7, and there are putative pseudogenes on other chromosomes.

      Images

      Western Blot analysis of A172, hela and hepg2 cell using IGF2BP3 Polyclonal Antibody at dilution of 1:200

      • Show all (0)
      • Reviews (0)
      • Q&A (0)
      ... Show All Show Less
      MSDS for ELISA

      Browsing History


        People Also Bought