IRF3 Polyclonal Antibody

Uniprot : Q14653
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
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    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-40145

      Synonyms:IIAE7,Interferon regulatory factor 3,IRF 3,IRF-3,IRF3,IRF3,MGC94729

      Size:
      • 20μL
      • 60μL
      • 120μL
      • 200μL
      Qty:
      - +
      Price: $60

      Host: Rabbit

      Reactivity: H,R

      Applications: WB,IHC

      Lead Time: 7~10 daysWelcome to order from local distributors.

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      Overview

      Synonyms IIAE7,Interferon regulatory factor 3,IRF 3,IRF-3,IRF3,IRF3,MGC94729
      Swissprot Q14653
      Source Rabbit
      Reactivity Human,Rat
      Immunogen Recombinant human Interferon regulatory factor 3 protein
      Application WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R217)
      Recommended dilution WB 1:500-1:1000, IHC 1:50-1:100
      Concentration 2 mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Cytoplasm. Nucleus. Shuttles between cytoplasmic and nuclear compartments, with export being the prevailing effect. When activated, IRF3 interaction with CREBBP prevents its export to the cytoplasm.
      Tissue specificity Expressed constitutively in a variety of tissues.
      Isotype IgG
      Purification Affinity purification
      Conjugation Unconjugated
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.05% Proclin300 and 50% glycerol, pH7.4.
      Background This gene encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

      Images

      polyclonal antibody-Elabscience

      Western Blot analysis of HeLa cells using IRF3 Polyclonal Antibody at dilution of 1:600

      polyclonal antibody-Elabscience

      Immunohistochemistry of paraffin-embedded Rat kidney using IRF3 Polyclonal Antibody at dilution of 1:50

      Immunohistochemistry analysis of paraffin-embedded Human Tonsil using IRF3 Polyclonal Antibody(Elabscience® Product Detected by Lifespan).

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