IRF6 Polyclonal Antibody

Uniprot : O14896
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
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    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-14165

      Synonyms:Interferon regulatory factor 6,IRF 6,IRF-6,IRF6,IRF6,LPS,OFC 6,OFC6,OTTHUMP00000034677,OTTHUMP00000034678,PIT,PPS,PPS1,VWS,VWS1

      Size:
      • 20μL
      • 60μL
      • 120μL
      • 200μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H,M

      Applications: WB,IHC,ELISA

      Lead Time: 7~10 daysWelcome to order from local distributors.

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      Overview

      Synonyms Interferon regulatory factor 6,IRF 6,IRF-6,IRF6,IRF6,LPS,OFC 6,OFC6,OTTHUMP00000034677,OTTHUMP00000034678,PIT,PPS,PPS1,VWS,VWS1
      Swissprot O14896
      Source Rabbit
      Reactivity Human,Mouse
      Immunogen Recombinant protein of human IRF6
      Application WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213),ELISA
      Recommended dilution WB 1:200-1:1000, IHC 1:50-1:200
      Concentration 0.4 mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Nucleus. Cytoplasm. Translocates to nucleus in response to an activating signal.
      Tissue specificity Expressed in normal mammary epithelial cells. Expression is reduced or absent in breast carcinomas.
      Isotype IgG
      Purification Affinity purification
      Conjugation Unconjugated
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.05% sodium azide and 50% glycerol, PH7.4
      Background This gene encodes a member of the interferon regulatory transcription factor (IRF) family. Family members share a highly-conserved N-terminal helix-turn-helix DNA-binding domain and a less conserved C-terminal protein-binding domain. The encoded protein may be a transcriptional activator. Mutations in this gene can cause van der Woude syndrome and popliteal pterygium syndrome. Mutations in this gene are also associated with non-syndromic orofacial cleft type 6. Alternate splicing results in multiple transcript variants.

      Images

      Western Blot analysis of 231 cell, Mouse kidney and lung tissue using IRF6 Polyclonal Antibody at dilution of 1:400

      Immunohistochemistry of paraffin-embedded Human cervical cancer using IRF6 Polyclonal Antibody at dilution of 1:50

      Immunohistochemistry of paraffin-embedded Human lung cancer using IRF6 Polyclonal Antibody at dilution of 1:50

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