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MECOM Polyclonal Antibody

Cat:E-AB-19826
Manual MSDS

Price: $ 399

Price: $ 240

Price: $ 143

Price: $ 73

Size:
200μL 120μL 60μL 20μL
Quantity:
  • Host: Rabbit
  • Reactivity: Human; Mouse
  • Applications: IHC
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Product Details
Verified Samples Verified Samples in IHC:Human thyroid cancer
Dilution

IHC 1:40-1:200

Western Blot Operation Guide
Clonality Polyclonal
Immunogen Synthetic peptide of human MECOM
Abbre MECOM
Synonyms Ecotropic Virus Integration Site 1 Protein Homolog;MDS1 And EVI1 Complex Locus Protein;PR Domain 3;EVI1;MDS1;MDS1 And EVI1 Complex Locus Protein EVI1;MDS1 And EVI1 Complex Locus Protein MDS1;Ecotropic Viral Integration Site 1;Myelodysplasia Syndrome 1 Protein;Zinc Finger Protein Evi1;Oncogene EVI1;AML1-EVI-1;MDS1-EVI1;RUSAT2;KMT8E;PRDM3
Swissprot
Cellular Localization Cytoplasm, Nucleus
Concentration 1.68 mg/mL
Buffer PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Purification Method Antigen affinity purification
Research Areas Cancer; Epigenetics and Nuclear Signaling
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping Ice bag
background The protein encoded by this gene is a transcriptional regulator and oncoprotein that may be involved in hematopoiesis, apoptosis, development, and cell differentiation and proliferation. The encoded protein can interact with CTBP1, SMAD3, CREBBP, KAT2B, MAPK8, and MAPK9. This gene can undergo translocation with the AML1 gene, resulting in overexpression of this gene and the onset of leukemia. Several transcript variants encoding a few different isoforms have been found for this gene.