MMA Focurose 6HP

    • MMA-6HP-Elabscience
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    • MMA-6HP-Elabscience
    • MMA-6HP-Elabscience

      Catalog number:E-CM-IE20

      Size:
      • 25mL
      • 100mL
      • 300mL
      • 500mL
      • 1L
      Qty:
      - +
      Price: Inquire

      Matrix: Highly cross-linked 6% agarose

      Particle size range: 25-45 µm

      Average particle size: 37 µm

      Pressure: ≤ 0.3 MPa

      Lead Time: 7~10 daysWelcome to order from local distributors.

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      Product introduction

      MMA-6HP is a kind of multi-mode biological separation medium, which is mainly used for moderate and fine purification of monoclonal antibody (to remove the Protein A* after Protein A purification, dimers, polymers, host cell proteins, nucleic acids), and it can also be used for fine purification of other biological molecules (to remove dimers, polymers, host cell proteins, nucleic acids, etc).

      * Micro amount of Protein A may drop off in the process of operating Protein A-4HF.


      Figure 1: The ligand of MMA-6HP is a kind of multi-mode ligand, it has many types of interaction with target molecules, mainly include the ionic interaction (strong anion interaction), and followed by hydrogen binding and hydrophobic interaction, etc.

       

      Advantages

      1. Combine with charged molecules under high conductance conditions. The sample is no longer restricted by electrical conductivity and can processed ion exchange without pretreatment.

      2. High binding capacity. It has a higher processing capacity under flowthrough mode.

      3. It has a new selectivity compared with the traditional ion exchange media.

      4. High resolution.

       

      Performance index

      Matrix

      Highly cross-linked 6% agarose

      Particle size range

      25-45 µm

      Average particle size

      37 µm

      Media type

      Strong anion exchanger

      Ionic capacity

      130-200 µmol Cl-/mL (media)

      Binding capacity

      95mg BSA/mL (media)

      pH stability

      2-14 (short term)

      3-12 (working)

      3-12 (long term)

      Chemical stability

      All of the commonly used buffers, 1M acetate, 1M NaOH, 70% Ethanol, 8M urea, 6M guanidine hydrochloride. Avoid of oxidizing agent and anionic detergent

      Flow rate

       150-250 cm/h

      (0.3MPa, XK16/40. Column bed height:30 cm)

      Pressure

      0.3 MPa

      Storage buffer

      20% Ethanol

      Storage temperature

      4~30


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