MSH3 Polyclonal Antibody

Uniprot : P20585
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
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    >
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-14225

      Synonyms:Divergent upstream protein,DNA mismatch repair protein,DNA mismatch repair protein Msh 3,DNA mismatch repair protein MSH3,DUC 1,DUC1,DUG,DUP,hMSH3,MGC163306,MGC163308,Mismatch repair protein 1,MRP 1,MRP1,MSH 3,MSH3,MSH3,MutS homolog 3 (E. coli),MutS homolog 3

      Size:
      • 20μL
      • 60μL
      • 120μL
      • 200μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H,M

      Applications: IHC,ELISA

      Lead Time: 7~10 daysWelcome to order from local distributors.

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      Overview

      Synonyms Divergent upstream protein,DNA mismatch repair protein,DNA mismatch repair protein Msh 3,DNA mismatch repair protein MSH3,DUC 1,DUC1,DUG,DUP,hMSH3,MGC163306,MGC163308,Mismatch repair protein 1,MRP 1,MRP1,MSH 3,MSH3,MSH3,MutS homolog 3 (E. coli),MutS homolog 3
      Swissprot P20585
      Source Rabbit
      Reactivity Human,Mouse
      Immunogen Recombinant protein of human MSH3
      Application IHC(Detection kit: E-IR-R213),ELISA
      Recommended dilution IHC 1:25-1:100
      Concentration 0.3 mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Nucleus,MutSbeta complex,nucleoplasm,Other locations:membrane
      Isotype IgG
      Purification Affinity purification
      Conjugation Unconjugated
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
      Background The protein encoded by this gene forms a heterodimer witHuman, MouseSH2 to form MutS beta, part of the post-replicative DNA mismatch repair system. MutS beta initiates mismatch repair by binding to a mismatch and then forming a complex witHuman, MouseutL alpha heterodimer. This gene contains a polymorphic 9 bp tandem repeat sequence in the first exon. The repeat is present 6 times in the reference genome sequence and 3-7 repeats have been reported. Defects in this gene are a cause of susceptibility to endometrial cancer.

      Images

      Immunohistochemistry of paraffin-embedded Human colon cancer tissue using MSH3 Polyclonal Antibody at dilution 1:30

      Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using MSH3 Polyclonal Antibody at dilution 1:30

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