MTDH Polyclonal Antibody (E-AB-62557)
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For research use only.
| Verified Samples |
Verified Samples in IHC: Rat brain, Human gastric, Mouse brain Verified Samples in IF: U2OS |
| Dilution | IHC 1:50-1:200, IF 1:50-1:200 |
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | IHC, IF |
| Clonality | Polyclonal |
| Immunogen | Recombinant fusion protein of human MTDH (NP_848927.2). |
| Abbre | MTDH |
| Synonyms | 3D3, AEG-1, AEG1, LYRIC, LYRIC/3D3, MTDH |
| Swissprot | |
| Cellular Localization | Endoplasmic reticulum membrane, Nucleus membrane, Cell junction, tight junction, Nucleus, nucleolus, Cytoplasm, perinuclear region, In epithelial cells, recruited to tight junctions (TJ) during the maturation of the TJ complexes, A nucleolar staining may be due to nuclear targeting of an isoform lacking the transmembrane domain (By similarity), TNF-alpha causes translocation from the cytoplasm to the nucleus. |
| Concentration | 1 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
| background | MTDH (Metadherin) is a Protein Coding gene. Diseases associated with MTDH include Tongue Carcinoma and Gallbladder Adenocarcinoma. Among its related pathways are Gastric Cancer Network 2 and Validated targets of C-MYC transcriptional activation. Gene Ontology (GO) annotations related to this gene include double-stranded RNA binding. An important paralog of this gene is MAMSTR. |
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