MutL Protein Homolog 1(MLH1) Monoclonal Antibody

Name: MutL Protein Homolog 1(MLH1) Monoclonal Antibody
Brand: Elabscience
SKU: PA6124
Price: 200 USD
Availability: InStock

Catalog number:PA6124

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Price: $200

Reactivity: Human

Applications: IHC-P

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Size	3mL/6mL(Ready-to-Use) 100μL/200μL(Concentrated)
Source	Mouse
Clone No.	YN01116m
Reactivity	Human
Application	IHC-P
Background	MutL Protein Homolog 1(MLH1) is a mismatch repair gene, which is located on p-arm 21.3 of chromosome 3. And DNA mismatch repair is very necessary to maintain the integrity of genetic information. The change of microsatellite reproducibility is caused by the slippage of the hinge misalignment during DNA replication, also known as microsatellite instability. The defects of these DNA repair pathways are related to some human tumors. The mutant mismatch repair gene is often expressed in patients with high frequency microsatellite instability (MSI-H), which is related to autosomal dominant genetic diseases.

Immunohistochemistry of paraffinembedded Human colon cancer tissue with MutL Protein Homolog 1(MLH1) Monoclonal Antibody(Antigen repaired by EDTA).

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Cat. No	PA6124
Application