MutS Protein Homolog 6(MSH6) Monoclonal Antibody
Price: $ 470
Price: $ 270
Price: $ 365
Price: $ 200
Size:
200μL
100μL
6mL
3mL
Quantity:
- Host: Mouse
- Reactivity: Human
- Applications: IHC-P
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Product Details
Verified Samples |
Verified Samples in IHC:Human colon cancer tissue |
Clonality | Monoclonal |
Size | 3mL/6mL(Ready-to-Use);100μL/200μL(Concentrated) |
Abbre | MutS Protein Homolog 6(MSH6) |
Synonyms | MSH2,COCA1,FCC1,HNPCC,HNPCC1,LCFS2 |
Swissprot | |
Cellular Localization | Nucleus |
Clone No. | YN01136m |
Conjugation | Unconjugated |
Storage | The concentrated should be stored at -20°C protecting from light,The RTU should be stored at 2~8°C protecting from light (Do not freeze).Valid for 12 months. |
Shipping | Ice bag |
background | MSH6, known as MutS homolog 6 (E.coli), is a mismatch repair gene. DNA mismatch repair is very necessary to maintain the integrity of genetic information. The change of microsatellite's reproducibility is caused by the slippage of the hinge misalignment during DNA replication, which is also called microsatellite instability. Mutant mismatch repair proteins are often expressed in patients with high frequency microsatellite instability (MSI-H), which is related to autosomal dominant inheritance, also known as hereditary nonpolyposis colorectal cancer (HNPCC), and sporadic (MSI-H) colorectal cancer. MLH1, MSH2, MSH6 antibodies can be used to screen the disease in patients and their families. |
Experiment Operation Video
Protocols
• Western Blot Guide
• Immunohistochemistry Guide for Slide-mounted Paraffin Sections
• Immunofluorescence Guide
• Immunohistochemistry Troubleshooting Tips
• Western Blot Troubleshooting Tips
• Immunofluorescence Troubleshooting Tips
• Comparison of Protein Separation Linear Range
• ImmunoPrecipitation Protocol