OGT Polyclonal Antibody

Uniprot: O15294
  • polyclonal antibody-Elabscience
  • polyclonal antibody-Elabscience
  • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
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    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-36533

      Synonyms:FLJ23071,GlcNAc transferase,HRNT1,MGC22921,O GlcNAc,O GlcNAc transferase p110 subunit,O GlcNAc transferase subunit p110,O linked N acetylglucosamine (GlcNAc) transferase (UDP N acetylglucosamine:polypeptide N acetylglucosaminyl transferase),O linked N acetylglucosamine (GlcNAc) transferase,O linked N acetylglucosamine transferase 110 kDa subunit,O-GlcNAc transferase subunit p110,O-linked N-acetylglucosamine transferase 110 kDa subunit,ogt,OGT1,UDP N acetylglucosamine peptide N acetylglucosaminyltransferase 110 kDa subunit,UDP N acetylglucosamine peptide N acetylglucosaminyltransferase GlcNAc transferase,UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit,UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase,Uridinediphospho N acetylglucosamine:polypeptide beta N acetylglucosaminyl transferase

      Size:
      • 20μL
      • 60μL
      • 120μL
      • 200μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H,M,R

      Applications: WB,ELISA

      Lead Time: 7~10 daysWelcome to order from local distributors.

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      Overview

      Synonyms FLJ23071,GlcNAc transferase,HRNT1,MGC22921,O GlcNAc,O GlcNAc transferase p110 subunit,O GlcNAc transferase subunit p110,O linked N acetylglucosamine (GlcNAc) transferase (UDP N acetylglucosamine:polypeptide N acetylglucosaminyl transferase),O linked N acetylglucosamine (GlcNAc) transferase,O linked N acetylglucosamine transferase 110 kDa subunit,O-GlcNAc transferase subunit p110,O-linked N-acetylglucosamine transferase 110 kDa subunit,ogt,OGT1,UDP N acetylglucosamine peptide N acetylglucosaminyltransferase 110 kDa subunit,UDP N acetylglucosamine peptide N acetylglucosaminyltransferase GlcNAc transferase,UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit,UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase,Uridinediphospho N acetylglucosamine:polypeptide beta N acetylglucosaminyl transferase
      Swissprot O15294
      Source Rabbit
      Reactivity Human,Mouse,Rat
      Immunogen Synthesized peptide derived from human OGT Polyclonal
      Application WB,ELISA
      Recommended dilution WB 1:500-2000, ELISA 1:10000-20000
      Concentration 1mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Cytoplasm. Nucleus. Mostly in the nucleus.
      Tissue specificity Highly expressed in pancreas and to a lesser extent in skeletal muscle, heart, brain and placenta. Present in trace amounts in lung and liver.
      Isotype IgG
      Purification Affinity purification
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.02% sodium azide,0.5% BSA and 50% glycerol pH 7.4.
      Background OGT (O-Linked N-Acetylglucosamine (GlcNAc) Transferase) is a Protein Coding gene. Diseases associated with OGT include Adams-Oliver Syndrome and Spinocerebellar Ataxia 10. Among its related pathways are Circadian rythm related genes and Deubiquitination. GO annotations related to this gene include identical protein binding and phosphatidylinositol-3,4,5-trisphosphate binding. An important paralog of this gene is TMTC3.This gene encodes a glycosyltransferase that catalyzes the addition of a single N-acetylglucosamine in O-glycosidic linkage to serine or threonine residues. Since both phosphorylation and glycosylation compete for similar serine or threonine residues, the two processes may compete for sites, or they may alter the substrate specificity of nearby sites by steric or electrostatic effects. The protein contains multiple tetratricopeptide repeats that are required for optimal recognition of substrates. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

      Images

      Western Blot analysis of HepG2 cells using OGT Polyclonal Antibody at dilution of 1:1000.

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