P73 Polyclonal Antibody

Uniprot : O15350
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
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    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-14274

      Synonyms:p53 like transcription factor,p53 related protein,p53-like transcription factor,p53-related protein,p73,P73,TP73,Tumor protein p73

      Size:
      • 20μL
      • 60μL
      • 120μL
      • 200μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H,M

      Applications: WB,ELISA

      Lead Time: 7~10 daysWelcome to order from local distributors.

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      Overview

      Synonyms p53 like transcription factor,p53 related protein,p53-like transcription factor,p53-related protein,p73,P73,TP73,Tumor protein p73
      Swissprot O15350
      Source Rabbit
      Reactivity Human,Mouse
      Immunogen Recombinant protein of human TP73
      Application WB(Detection kit: E-IR-R304),ELISA
      Recommended dilution WB 1:200-1:1000
      Concentration 0.2 mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Nucleus. Accumulates in the nucleus in response to DNA damage.
      Tissue specificity Expressed in striatal neurons of patients with Huntington disease (at protein level). Brain, kidney, placenta, colon, heart, liver, spleen, skeletal muscle, prostate, thymus and pancreas. Highly expressed in fetal tissue.
      Isotype IgG
      Purification Affinity purification
      Conjugation Unconjugated
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.05% sodium azide and 50% glycerol, PH7.4
      Background This gene encodes a member of the p53 family of transcription factors involved in cellular responses to stress and development. It maps to a region on chromosome 1p36 that is frequently deleted in neuroblastoma and other tumors, and thought to contain multiple tumor suppressor genes. The demonstration that this gene is monoallelically expressed (likely from the maternal allele), supports the notion that it is a candidate gene for neuroblastoma. Many transcript variants resulting from alternative splicing and/or use of alternate promoters have been found for this gene, but the biological validity and the full-length nature of some variants have not been determined.

      Images

      Western Blot analysis of Human fetal muscle tissue and 231 cell using P73 Polyclonal Antibody at dilution of 1:300

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