P-Cadherin Polyclonal Antibody

Uniprot : P22223
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
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    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-32519

      Synonyms:CADH3,Cadherin 3,Cadherin 3 precursor,Cadherin 3 type 1,Cadherin-3,Cadp,Calcium dependent adhesion protein placental,CDH 3,CDH3,CDH3 protein,CDHP,HJMD,P cadherin (placental),P-cadherin,PCAD,Placental cadherin

      Size:
      • 20 μL
      • 60 μL
      • 120 μL
      • 200 μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H

      Applications: WB,IHC-p,ELISA

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      Overview

      Synonyms CADH3,Cadherin 3,Cadherin 3 precursor,Cadherin 3 type 1,Cadherin-3,Cadp,Calcium dependent adhesion protein placental,CDH 3,CDH3,CDH3 protein,CDHP,HJMD,P cadherin (placental),P-cadherin,PCAD,Placental cadherin
      Swissprot P22223
      Source Rabbit
      Reactivity Human
      Immunogen Synthesized peptide derived from the N-terminal region of human P-cadherin
      Application WB(Detection kit: E-IR-R304),IHC-p(Detection kit: E-IR-R213),ELISA
      Recommended dilution WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:10000
      Concentration 1mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Cell membrane.
      Tissue specificity Expressed in some normal epithelial tissues and in some carcinoma cell lines.
      Isotype IgG
      Purification Affinity purification
      Conjugation Unconjugated
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
      Background This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. This gene is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in this gene have been associated with congential hypotrichosis with juvenile macular dystrophy.

      Images

      Western Blot analysis of K562 cells with P-cadherin Polyclonal Antibody.

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