PARK7 Polyclonal Antibody

Uniprot : Q99497
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
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    >
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-14284

      Synonyms:CAP1,DJ-1,DJ1,DJ1 protein,Epididymis secretory sperm binding protein Li 67p,FLJ27376,FLJ34360,FLJ92274,HEL S 67p,Oncogene DJ1,OTTHUMP00000001348,OTTHUMP00000001349,OTTHUMP00000001350,OTTHUMP00000001351,PARK7,PARK7,Parkinson disease (autosomal recessive,early onset) 7,Parkinson disease protein 7,Parkinson protein 7,Protein DJ-1,SP22

      Size:
      • 20μL
      • 60μL
      • 120μL
      • 200μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H,M,R

      Applications: WB,ELISA

      Lead Time: 7~10 daysWelcome to order from local distributors.

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      Overview

      Synonyms CAP1,DJ-1,DJ1,DJ1 protein,Epididymis secretory sperm binding protein Li 67p,FLJ27376,FLJ34360,FLJ92274,HEL S 67p,Oncogene DJ1,OTTHUMP00000001348,OTTHUMP00000001349,OTTHUMP00000001350,OTTHUMP00000001351,PARK7,PARK7,Parkinson disease (autosomal recessive,early onset) 7,Parkinson disease protein 7,Parkinson protein 7,Protein DJ-1,SP22
      Swissprot Q99497
      Source Rabbit
      Reactivity Human,Mouse,Rat
      Immunogen Recombinant protein of human PARK7
      Application WB(Detection kit: E-IR-R304),ELISA
      Recommended dilution WB 1:200-1:1000
      Concentration 0.1 mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Cytoplasm. Nucleus. Mitochondrion. Under normal conditions, located predominantly in the cytoplasm and, to a lesser extent, in the nucleus and mitochondrion. Translocates to the mitochondrion and subsequently to the nucleus in response to oxidative stress and exerts an increased cytoprotective effect against oxidative damage. Detected in tau inclusions in brains from neurodegenerative disease patients.
      Tissue specificity Highly expressed in pancreas, kidney, skeletal muscle, liver, testis and heart. Detected at slightly lower levels in placenta and brain. Detected in astrocytes, Sertoli cells, spermatogonia, spermatids and spermatozoa.
      Isotype IgG
      Purification Affinity purification
      Conjugation Unconjugated
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.05% sodium azide and 50% glycerol, PH7.4
      Background The product of this gene belongs to the peptidase C56 family of proteins. It acts as a positive regulator of androgen receptor-dependent transcription. It may also function as a redox-sensitive chaperone, as a sensor for oxidative stress, and it apparently protects neurons against oxidative stress and cell death. Defects in this gene are the cause of autosomal recessive early-onset Parkinson disease 7. Two transcript variants encoding the same protein have been identified for this gene.

      Images

      Western Blot analysis of HT-29 cell using PARK7 Polyclonal Antibody at dilution of 1:200

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