PCDHB16 Polyclonal Antibody

Uniprot : Q9NRJ7
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
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    >
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-14448

      Synonyms:Cadherin ME1,KIAA1621,ME 1,ME1,PCDBG,PCDH 3X,PCDH beta16,PCDH-beta-16,PCDH3X,PCDHB 16,PCDHB 8a,PCDHB16,PCDHB8a,PCDHbeta 16,Protocadherin 3x,Protocadherin beta 16,Protocadherin beta 8a,Protocadherin beta-16,Protocadherin-3X,Protocadherin3x

      Size:
      • 20μL
      • 60μL
      • 120μL
      • 200μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H

      Applications: IHC,ELISA

      Lead Time: 7~10 daysWelcome to order from local distributors.

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      Overview

      Synonyms Cadherin ME1,KIAA1621,ME 1,ME1,PCDBG,PCDH 3X,PCDH beta16,PCDH-beta-16,PCDH3X,PCDHB 16,PCDHB 8a,PCDHB16,PCDHB8a,PCDHbeta 16,Protocadherin 3x,Protocadherin beta 16,Protocadherin beta 8a,Protocadherin beta-16,Protocadherin-3X,Protocadherin3x
      Swissprot Q9NRJ7
      Source Rabbit
      Reactivity Human
      Immunogen Recombinant protein of human PCDHB16
      Application IHC(Detection kit: E-IR-R213),ELISA
      Recommended dilution IHC 1:25-1:100
      Concentration 0.3 mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Membrane.
      Isotype IgG
      Purification Affinity purification
      Conjugation Unconjugated
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.05% sodium azide and 50% glycerol, PH7.4
      Background This gene is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The beta cluster contains 16 genes and 3 pseudogenes, each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily. The extracellular domains interact in a homophilic manner to specify differential cell-cell connections. Unlike the alpha and gamma clusters, the transcripts from these genes are made up of only one large exon, not sharing common 3' exons as expected. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins. Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific cell-cell neural connections.

      Images

      Immunohistochemistry of paraffin-embedded Human brain tissue using PCDHB16 Polyclonal Antibody at dilution 1:30

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