PE/Cyanine5 Anti-Human CD127/IL-7RA Antibody[A019D5] E-AB-F1152G

Uniprot : P16871
  • Host: Mouse
  • Applications: FCM
  • Isotype: Mouse IgG1, κ

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Antigen Details

Alternate Names Interleukin-7 receptor subunit alpha,IL-7RA,CDw127,CD127,IL-7Rα
Swissprot P16871
References
1. Sudo T, et al. 1993. P. Natl. Acad. Sci. USA 90:9125.
2. He YW and Malek TR. 1998. Crit. Rev. Immunol. 18:503.
3. Huster KM, et al. 2004. P. Natl. Acad. Sci. USA 101:5610.
4. Pillai M, et al. 2004. Leukemia Lymphoma 45:2403.
5. Morrissey PJ, et al. 1989. J. Exp. Med. 169:707.
6. Liu W, et al. 2006. J. Exp. Med. 203:1701.

Product Details

Form Liquid
Clone No. A019D5(See Other Available Formats)
Host Mouse
Isotype Mouse IgG1, κ
Isotype Control PE/Cyanine5 Mouse IgG1, κ Isotype Control[MOPC-21] [Product E-AB-F09792G]
Reactivity Human
Application FCM (See the Application Description)
Storage Buffer PBS with 0.05% Proclin300, 1% BSA
Recommended Use Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. The amount of the reagent is suggested to be used 5 μL of antibody per test (million cells in 100 μL staining volume or per 100 μL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Shipping Biological ice pack at 4℃
Stability & Storage Keep as concentrated solution.
Store at 2~8℃ and protected from prolonged exposure to light. Do not freeze.
Centrifuge before opening to ensure complete recovery of vial contents.
This product is guaranteed up to one year from purchase.
Conjugation PE/Cyanine5

Background

CD127 is a 60-90 kD type I transmembrane glycoprotein also known as IL-7 receptor α chain or IL-7Rα. It forms a heterodimer with the common γ chain (γc or CD132) which is shared with the receptors for IL-2, IL-4, IL-9, IL-13, IL-15, and IL-21. CD127 is expressed on immature B cells through early pre-B stage cells, thymocytes (except CD4/CD8 double positive thymocytes), peripheral T cells, and bone marrow stromal cells. CD127 has been reported to be a useful marker for identifying memory and effector T cells. Studies have shown that CD127 expression is down-modulated on Treg cells. It can be used as a marker for differentiation of Treg and conventional T cells. The ligation of IL-7 with its receptor is important for stimulation of mature and immature T cells as well as immature B cell proliferation and development.

Protocols & Troubleshootings

Related Protocols Staining Cell Surface Targets for Flow Cytometry
Troubleshooting

Troubleshooting for Flow Cytometry

Alternative Formats

Cat.No. Product Name Sizes
E-AB-F1152C FITC Anti-Human CD127/IL-7RA Antibody[A019D5] E-AB-F1152C 20 Tests, 50 Tests, 100 Tests, 200 Tests
E-AB-F1152D PE Anti-Human CD127/IL-7RA Antibody[A019D5] E-AB-F1152D 20 Tests, 50 Tests, 100 Tests, 200 Tests
E-AB-F1152E APC Anti-Human CD127/IL-7RA Antibody[A019D5] E-AB-F1152E 20 Tests, 50 Tests, 100 Tests, 200 Tests
E-AB-F1152G PE/Cyanine5 Anti-Human CD127/IL-7RA Antibody[A019D5] E-AB-F1152G 20 Tests, 50 Tests, 100 Tests, 200 Tests
E-AB-F1152H PE/Cyanine7 Anti-Human CD127/IL-7RA Antibody[A019D5] E-AB-F1152H 20 Tests, 50 Tests, 100 Tests, 200 Tests
E-AB-F1152I PE/Cyanine5.5 Anti-Human CD127/IL-7RA Antibody[A019D5] E-AB-F1152I 20 Tests, 50 Tests, 100 Tests, 200 Tests
E-AB-F1152J PerCP/Cyanine5.5 Anti-Human CD127/IL-7RA Antibody[A019D5] E-AB-F1152J 20 Tests, 50 Tests, 100 Tests, 200 Tests
E-AB-F1152L AF488 Anti-Human CD127/IL-7RA Antibody[A019D5] E-AB-F1152L 20 Tests, 50 Tests, 100 Tests, 200 Tests
E-AB-F1152M AF647 Anti-Human CD127/IL-7RA Antibody[A019D5] E-AB-F1152M 20 Tests, 50 Tests, 100 Tests, 200 Tests

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