PERK Polyclonal Antibody

Uniprot : Q9NZJ5
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    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
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    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-34095

      Synonyms:DKFZp781H1925,E2AK3,EC 2.7.11.1,Eif2ak3,Eukaryotic translation initiation factor 2 alpha kinase 3,Eukaryotic translation initiation factor 2-alpha kinase 3,Heme regulated EIF2 alpha kinase,HRI,HsPEK,Pancreatic eIF2 alpha kinase,Pancreatic eIF2-alpha kinase,PEK,PRKR like endoplasmic reticulum kinase,PRKR-like endoplasmic reticulum kinase,WRS

      Size:
      • 20 μL
      • 60 μL
      • 120 μL
      • 200 μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H,M,R

      Applications: IHC-p,IF,ELISA

      Lead Time: 2 daysWelcome to order from local distributors.

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      Overview

      Synonyms DKFZp781H1925,E2AK3,EC 2.7.11.1,Eif2ak3,Eukaryotic translation initiation factor 2 alpha kinase 3,Eukaryotic translation initiation factor 2-alpha kinase 3,Heme regulated EIF2 alpha kinase,HRI,HsPEK,Pancreatic eIF2 alpha kinase,Pancreatic eIF2-alpha kinase,PEK,PRKR like endoplasmic reticulum kinase,PRKR-like endoplasmic reticulum kinase,WRS
      Swissprot Q9NZJ5
      Source Rabbit
      Reactivity Human,Mouse,Rat
      Immunogen Synthesized peptide derived from human PERK around the non-phosphorylation site of Thr981.
      Application IHC-p(Detection kit: E-IR-R213),IF,ELISA
      Recommended dilution IHC 1:100-1:300, IF 1:50-1:200, ELISA 1:40000
      Concentration 1mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Endoplasmic reticulum membrane.
      Tissue specificity Ubiquitous. A high level expression is seen in secretory tissues.
      Isotype IgG
      Purification Affinity purification
      Conjugation Unconjugated
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
      Background Phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2 (EIF2), leading to its inactivation and thus to a rapid reduction of translational initiation and repression of global protein synthesis. Serves as a critical effector of unfolded protein response (UPR)-induced G1 growth arrest due to the loss of cyclin D1.

      Images

      Immunohistochemistry of paraffin-embedded Human stomach tissue using PERK Polyclonal Antibody at dilution of 1:200.

      Immunohistochemistry of paraffin-embedded Human stomach cancer tissue using PERK Polyclonal Antibody at dilution of 1:200.

      Immunofluorescence analysis of Rat spleen tissue using PERK Polyclonal Antibody at dilution of 1:200.

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