PIAS3 Polyclonal Antibody
Price: $ 399
Price: $ 240
Price: $ 143
Price: $ 73
Size:
200μL
120μL
60μL
20μL
Quantity:
- Host: Rabbit
- Reactivity: Human; Mouse; Rat
- Applications: IHC
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Product Details
Verified Samples |
Verified Samples in IHC:Human liver cancer,Human ovarian cancer |
Dilution |
IHC 1:40-1:200 Western Blot Operation Guide |
Clonality | Polyclonal |
Immunogen | Synthetic peptide of human PIAS3 |
Abbre | PIAS3 |
Synonyms | E3 SUMO protein ligase PIAS 3;E3 SUMO protein ligase PIAS3;E3 SUMO-protein ligase PIAS3;FLJ14651;OTTHUMP00000015586;OTTHUMP00000015587;PIAS 3;Pias3;PIAS3 protein;PIAS3;Protein inhibitor of activated STAT 3;Protein inhibitor of activated STAT protein 3;Protein inhibitor of activated STAT3;Zinc finger MIZ type containing 5;ZMIZ 5;ZMIZ5 |
Swissprot | |
Cellular Localization | Cytoplasm. Nucleus. Nucleus speckle. Colocalizes with MITF in the nucleus. Colocalizes with GFI1 in nuclear dots. Colocalizes with SUMO1 in nuclear granules. |
Concentration | 1.1 mg/mL |
Buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
Purification Method | Antigen affinity purification |
Research Areas | Cancer; Cell Biology; Epigenetics and Nuclear Signaling |
Conjugation | Unconjugated |
Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
Shipping | Ice bag |
background | This gene encodes a member of the PIAS [protein inhibitor of activated STAT (signal transducer and activator of transcription)] family of transcriptional modulators. The protein functions as a SUMO (small ubiquitin-like modifier)-E3 ligase which catalyzes the covalent attachment of a SUMO protein to specific target substrates. It directly binds to several transcription factors and either blocks or enhances their activity. Alternatively spliced transcript variants of this gene have been identified, but the full-length nature of some of these variants has not been determined. |
Experiment Operation Video
Protocols
• Western Blot Guide
• Immunohistochemistry Guide for Slide-mounted Paraffin Sections
• Immunofluorescence Guide
• Immunohistochemistry Troubleshooting Tips
• Western Blot Troubleshooting Tips
• Immunofluorescence Troubleshooting Tips
• Comparison of Protein Separation Linear Range
• ImmunoPrecipitation Protocol