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PIAS3 Polyclonal Antibody

Cat:E-AB-19322
Manual MSDS

Price: $ 399

Price: $ 240

Price: $ 143

Price: $ 73

Size:
200μL 120μL 60μL 20μL
Quantity:
  • Host: Rabbit
  • Reactivity: Human; Mouse; Rat
  • Applications: IHC
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Product Details
Verified Samples Verified Samples in IHC:Human liver cancer,Human ovarian cancer
Dilution

IHC 1:30-1:150

Western Blot Operation Guide
Clonality Polyclonal
Immunogen Synthetic peptide of human PIAS3
Abbre PIAS3
Synonyms E3 SUMO protein ligase PIAS 3;E3 SUMO protein ligase PIAS3;E3 SUMO-protein ligase PIAS3;FLJ14651;OTTHUMP00000015586;OTTHUMP00000015587;PIAS 3;Pias3;PIAS3 protein;PIAS3;Protein inhibitor of activated STAT 3;Protein inhibitor of activated STAT protein 3;Protein inhibitor of activated STAT3;Zinc finger MIZ type containing 5;ZMIZ 5;ZMIZ5
Swissprot
Cellular Localization Cytoplasm. Nucleus. Nucleus speckle. Colocalizes with MITF in the nucleus. Colocalizes with GFI1 in nuclear dots. Colocalizes with SUMO1 in nuclear granules.
Concentration 0.6 mg/mL
Buffer PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
Purification Method Antigen affinity purification
Research Areas Cancer; Cell Biology; Epigenetics and Nuclear Signaling
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping Ice bag
background This gene encodes a member of the PIAS [protein inhibitor of activated STAT (signal transducer and activator of transcription)] family of transcriptional modulators. The protein functions as a SUMO (small ubiquitin-like modifier)-E3 ligase which catalyzes the covalent attachment of a SUMO protein to specific target substrates. It directly binds to several transcription factors and either blocks or enhances their activity. Alternatively spliced transcript variants of this gene have been identified, but the full-length nature of some of these variants has not been determined.