POSTN Polyclonal Antibody

Uniprot : Q15063
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
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    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-40278

      Synonyms:Fasciclin-I like,MGC119510,MGC119511,OSF 2,OSF-2,OSF2,Osteoblast specific factor 2 (fasciclin I like),Osteoblast specific factor 2,Osteoblast specific factor,Osteoblast-specific factor 2,PDLPOSTN,Periodontal ligament specific periostin,Periostin,Periostin isoform thy2,Periostin isoform thy4,Periostin isoform thy6,Periostin isoform thy8,Periostin osteoblast specific factor,PN,POSTN,POSTN,RP11 412K4.1

      Size:
      • 20μL
      • 60μL
      • 120μL
      • 200μL
      Qty:
      - +
      Price: $60

      Host: Rabbit

      Reactivity: H

      Applications: IHC

      Lead Time: 7~10 daysWelcome to order from local distributors.

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      Overview

      Synonyms Fasciclin-I like,MGC119510,MGC119511,OSF 2,OSF-2,OSF2,Osteoblast specific factor 2 (fasciclin I like),Osteoblast specific factor 2,Osteoblast specific factor,Osteoblast-specific factor 2,PDLPOSTN,Periodontal ligament specific periostin,Periostin,Periostin isoform thy2,Periostin isoform thy4,Periostin isoform thy6,Periostin isoform thy8,Periostin osteoblast specific factor,PN,POSTN,POSTN,RP11 412K4.1
      Swissprot Q15063
      Source Rabbit
      Reactivity Human
      Immunogen Recombinant Human Periostin protein
      Application IHC(Detection kit: E-IR-R213)
      Recommended dilution IHC 1:100-1:200
      Concentration 0.79mg/mL

      Properties

      Cellular localization Secreted,extracellular matrix,Golgi apparatus
      Tissue specificity Widely expressed with Highest levels in aorta, stomach, lower gastrointestinal tract, placenta, uterus and breast. Up-regulated in epithelial ovarian tumors. Not expressed in normal ovaries. Also highly expressed at the tumor periphery of lung carcinoma tissue but not within the tumor. Overexpressed in breast cancers.
      Isotype IgG
      Purification Affinity Purification
      Conjugation Unconjugated
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.05% Proclin300, 50% glycerol, pH7.3.
      Background Periostin (POSTN,PN),originally named as osteoblast-specific factor 2 (OSF-2),is a 90-kDa secreted protein which is now classified as a matricellular protein. It is present in a wide variety of normal adult tissues and fetal tissues,and has a role in bone,tooth and heart development and function. Studies show that periostin is overexpressed in a broad range of human cancer types,includidng lung,ovary,breast and colon cancers. Recent evidence reveals that periostin is expressed by fibroblasts in the normal tissue and in the stroma of the primary tumour,and it is required to allow cancer stem cell maintenance.

      Images

      Immunohistochemistry of paraffin-embedded Human carcinoma of Colon using POSTN Polyclonal Antibody at dilution of 1:100(100×)

      Immunohistochemistry of paraffin-embedded Human carcinoma of Colon using POSTN Polyclonal Antibody at dilution of 1:100(400×)

      Immunohistochemistry of paraffin-embedded Human breast using POSTN Polyclonal Antibody at dilution of 1:100

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