PRKG2 Polyclonal Antibody

Uniprot: Q13237
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
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    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-30905

      Synonyms:CGK 2,cGK2,cGKII,cGMP dependent protein kinase 2,cGMP-dependent protein kinase 2,cGMP-dependent protein kinase II,KGP2,PRKG 2,PRKG2,PRKGR2,Protein kinase,cGMP dependent,type II,Type II cGMP dependent protein kinase

      Size:
      • 20μL
      • 60μL
      • 120μL
      • 200μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H,M,R

      Applications: WB,IHC-p,ELISA

      Lead Time: 7~10 daysWelcome to order from local distributors.

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      Overview

      Synonyms CGK 2,cGK2,cGKII,cGMP dependent protein kinase 2,cGMP-dependent protein kinase 2,cGMP-dependent protein kinase II,KGP2,PRKG 2,PRKG2,PRKGR2,Protein kinase,cGMP dependent,type II,Type II cGMP dependent protein kinase
      Swissprot Q13237
      Source Rabbit
      Reactivity Human,Mouse,Rat
      Immunogen Synthesized peptide derived from the Internal region of human cGKII
      Application WB,IHC-p,ELISA
      Recommended dilution WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:20000
      Concentration 1mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Cytosol,Nucleus,nuclear membrane,Plasma Membrane,apical plasma membrane
      Tissue specificity Highly concentrated in brain, lung and intestinal mucosa.
      Isotype IgG
      Purification Affinity purification
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.02% sodium azide,0.5% BSA and 50% glycerol pH 7.4.
      Background cGKII (cGMP-dependent protein kinase type II) is a major receptor of intracellular cGMP and mediates a plethora of physiological responses. cGKII contains a conserved leucine zipper motif at the amino-terminus. It is expressed in small intestine, colon, prostate, and human brain tissues, and the cGKII gene maps to chromosome 4q13.1-q21.1. cGKII has been shown to regulate the ion transport system in the intestine. Myristoylation of the penultimate glycine in cGKII appears to be essential for directing cGKII to the membrane, since cGKII is devoid of any hydrophobic transmembrane domains. The translocation of cGKII from the cytosol to the membrane allows it to function properly in regulating intestinal ion transport.

      Images

      Western Blot analysis of Jurkat cells with PRKG2 Polyclonal Antibody

      Western Blot analysis of HuvEc cells with PRKG2 Polyclonal Antibody

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