PSMD2 Polyclonal Antibody

Uniprot : Q13200
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
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    >
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience
    • polyclonal antibody-Elabscience

      Catalog number:E-AB-14320

      Synonyms:26S proteasome non-ATPase regulatory subunit 2,26S proteasome regulatory subunit RPN1,26S proteasome regulatory subunit S2,26S proteasome subunit p97,55.11 protein,MGC14274,P97,Proteasome (prosome macropain) 26S subunit non ATPase 2,Proteasome 26S subunit,non-ATPase,2,Proteasome 26S,subunit 2,Protein 55.11,Psmd2,PSMD2,Rpn1,S2,TNFR associated protein 2,TRAP2,Tumor necrosis factor receptor associated protein 2,Tumor necrosis factor type 1 receptor-associated protein 2

      Size:
      • 20μL
      • 60μL
      • 120μL
      • 200μL
      Qty:
      - +
      Price: $69

      Host: Rabbit

      Reactivity: H,M,R

      Applications: WB,ELISA

      Lead Time: 7~10 daysWelcome to order from local distributors.

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      Overview

      Synonyms 26S proteasome non-ATPase regulatory subunit 2,26S proteasome regulatory subunit RPN1,26S proteasome regulatory subunit S2,26S proteasome subunit p97,55.11 protein,MGC14274,P97,Proteasome (prosome macropain) 26S subunit non ATPase 2,Proteasome 26S subunit,non-ATPase,2,Proteasome 26S,subunit 2,Protein 55.11,Psmd2,PSMD2,Rpn1,S2,TNFR associated protein 2,TRAP2,Tumor necrosis factor receptor associated protein 2,Tumor necrosis factor type 1 receptor-associated protein 2
      Swissprot Q13200
      Source Rabbit
      Reactivity Human,Mouse,Rat
      Immunogen Recombinant protein of human PSMD2
      Application WB(Detection kit: E-IR-R304),ELISA
      Recommended dilution WB 1:200-1:1000
      Concentration 0.3 mg/mL
      Clonality Polyclonal

      Properties

      Cellular localization Cytosol,proteasome storage granule,Extracellular region or secreted,extracellular exosome,extracellular region,Nucleus,nucleoplasm,nucleus,Other locations:ficolin-1-rich granule lumen,membrane,proteasome accessory complex,proteasome complex,proteasome regulatory particle,proteasome regulatory particle, base subcomplex,secretory granule lumen
      Tissue specificity Found in skeletal muscle, liver, heart, brain, kidney, pancreas, lung and placenta.
      Isotype IgG
      Purification Affinity purification
      Conjugation Unconjugated
      Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
      Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
      Background The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the non-ATPase subunits of the 19S regulator lid. In addition to participation in proteasome function, this subunit may also participate in the TNF signalling pathway since it interacts with the tumor necrosis factor type 1 receptor. A pseudogene has been identified on chromosome 1.

      Images

      Western Blot analysis of Jurkat cell using PSMD2 Polyclonal Antibody at dilution of 1:400

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