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RAD51 Polyclonal Antibody

Cat:E-AB-16750 Citations (2)
Manual MSDS
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Price: $ 399

Price: $ 240

Price: $ 143

Price: $ 73

Size:
200μL 120μL 60μL 20μL
Quantity:
  • Host: Rabbit
  • Reactivity: Human;Mouse
  • Applications: WB;IHC
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For research use only. Order now, ship in 3 days

Product Details
Verified Samples Verified Samples in WB:Hela
Verified Samples in IHC:Human brain,Human breast cancer
Dilution

WB 1:500-1:2000, IHC 1:25-1:100

Western Blot Operation Guide
Clonality Polyclonal
Immunogen Synthetic peptide of human RAD51
Abbre RAD51
Synonyms BRCA1/BRCA2 containing complex;subunit 5;BRCC 5;BRCC5;DNA repair protein RAD51 homolog 1;DNA repair protein rhp51;FANCR;hRAD51;HsRAD51;HsT16930;MRMV2;Rad 51;RAD51;RAD51 homolog (RecA homolog;E. coli) (S. cerevisiae);RAD51 homolog A;RAD51 homolog;RAD51 recombinase;RAD51;S. cerevisiae;homolog of;RAD51;RAD51A;RECA;RecA like protein;RecA;E. coli;homolog of;Recombination protein A
Swissprot
Calculated MW 37kDa
Cellular Localization Nucleus. Cytoplasm. Cytoplasm, perinuclear region. Mitochondrion matrix. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Colocalizes with RAD51AP1 and RPA2 to multiple nuclear foci upon induction of DNA damage. DNA damage induces an increase in nuclear levels. Together with FIGNL1, redistributed in discrete nuclear DNA damage-induced foci after ionizing radiation (IR) or camptothecin (CPT) treatment. Accumulated at sites of DNA damage in a SPIDR-dependent manner.
Concentration 0.5 mg/mL
Buffer PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method Affinity purification
Research Areas Cancer; Epigenetics and Nuclear Signaling
Conjugation Unconjugated
Storage Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Shipping Biological ice pack at 4 ℃
background The protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are highly similar to bacterial RecA and Saccharomyces cerevisiae Rad51, and are known to be involved in the homologous recombination and repair of DNA. This protein can interact with the ssDNA-binding protein RPA and RAD52, and it is thought to play roles in homologous pairing and strand transfer of DNA. This protein is also found to interact with BRCA1 and BRCA2, whicHuman, Mouseay be important for the cellular response to DNA damage.