Recombinant 2019-nCoV 3C-like Proteinase Protein (His Tag)(Active)

    • Recombinant 2019-nCoV 3C-like Proteinase Protein (His Tag)-Elabscience
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    • Recombinant 2019-nCoV 3C-like Proteinase Protein (His Tag)-Elabscience
    • Recombinant 2019-nCoV 3C-like Proteinase Protein (His Tag)-Elabscience

      Catalog number:PKSR030465

      Synonyms:M Proteinase; 3CL Proteinase

      Size:
      • 10µg
      • 50µg
      Qty:
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      Price: $220

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      Overview

      Synonyms M Proteinase; 3CL Proteinase
      Species Virus
      Expression_host E.coli
      Sequence Ser1-Gln306
      Accession YP_009725301.1
      Mol_Mass 36.1 kDa
      AP_Mol_Mass 33 kDa
      Tag N-6His
      Bio_Activity Measured by its ability to cleave a fluorogenic peptide substrate, Dabcyl-KTSAVLQSGFRKME-Edans (Synthetic).The specific activity is >13000pmol/min/mg.

      Properties

      Purity > 95 % as determined by reducing SDS-PAGE.
      Endotoxin < 1.0 EU per µg as determined by the LAL method.
      Storage Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
      Shipping This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt; store it immediately at<-20°C.
      Formulation Supplied as a 0.2 μM filtered solution of PBS, 1mM EDTA, 10% Glycerol, pH 7.4.
      Reconstitution Please refer to the printed manual for detailed information.

      Background

      The viral main proteinase (M pro , also called 3CL pro ), which controls the activities of the coronavirus replication complex. It functions as a cysteine protease engaging in the proteolytic cleavage of the viral precursor polyprotein to a series of functional proteins required for coronavirus replication and is considered as an appealing target for designing anti-SARS agents.

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