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Recombinant Human Activin RIIA/ACVR2A Protein (His Tag)

    • Recombinant Human Activin RIIA  / ACVR2A Protein (C-His)-Elabscience
    • Recombinant Protein-Elabscience
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    • Recombinant Human Activin RIIA  / ACVR2A Protein (C-His)-Elabscience
    • Recombinant Protein-Elabscience
    • Recombinant Human Activin RIIA  / ACVR2A Protein (C-His)-Elabscience
    • Recombinant Protein-Elabscience

      Catalog number:PKSH033783

      Synonyms:Activin Receptor Type-2A; Activin Receptor Type IIA; ACTR-IIA; ACTRIIA; ACVR2A; ACVR2;ACTRII

      Size:
      • 10μg
      • 50μg
      Qty:
      - +
      Price: $86

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      Overview

      Synonyms Activin Receptor Type-2A; Activin Receptor Type IIA; ACTR-IIA; ACTRIIA; ACVR2A; ACVR2;ACTRII
      Species Human
      Expression_host Human Cells
      Sequence Ala20-Pro134
      Accession P27037
      Mol_Mass 14.35 kDa
      AP_Mol_Mass 32 kDa
      Tag C-His

      Properties

      Purity > 95% as determined by reducing SDS-PAGE.
      Endotoxin < 1.0 EU per μg as determined by the LAL method.
      Storage Lyophilized protein should be stored at < -20℃, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7℃ for 2-7 days.Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
      Shipping This product is provided as lyophilized powder which is shipped with ice packs.
      Formulation Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
      Reconstitution Please refer to the printed manual for detailed information.

      Background

      Activin Receptor Type-2A is a protein that in humans is encoded by the ACVR2A gene. ACVR2A is an activin type 2 receptor. This gene encodes activin A type II receptor. Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. Type II receptors are considered to be constitutively active kinases.

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      MSDS for ELISA ISO 9001

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