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Recombinant Human ALK-1/ACVRL1 Protein (Fc Tag)

Cat:PKSH033782
Manual MSDS

Price: $ 111

Price: $ 37

Size:
50μg 10μg
Quantity:
  • Expression Host: HEK293 Cells
  • Accession: P37023
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Product Details
Synonyms Serine/Threonine-Protein Kinase Receptor R3;SKR3;Activin Receptor-Like Kinase 1;ALK-1;TGF-B Superfamily Receptor Type I;TSR-I;ACVRL1;ACVRLK1;ALK1;HHT;HHT2;ORW2;SKR3
Species Human
Expression Host HEK293 Cells
Sequence Asp22-Gln118
Accession P37023
Calculated Molecular Weight 37.6 kDa
Observed Molecular Weight 50-65 kDa
Tag C-Fc
Purity > 90 % as determined by reducing SDS-PAGE.
Endotoxin < 1.0 EU per μg of the protein as determined by the LAL method.
Storage Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping This product is provided as lyophilized powder which is shipped with ice packs.
Formulation Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution Please refer to the printed manual for detailed information.
Background Activin Receptor-Like Kinase 1 (ALK-1) is a type I cell-surface receptor for the TGF-βsuperfamily of ligands. ALK-1 has a high degree of similarity in serine-threonine kinase subdomains, a glycine and serine rich region preceding the kinase-domain, and a C-terminal tail with other activin receptor-like kinase proteins. The mutations of ALK-1 are associated with Rendu-Osler-Weber syndrome 2, this suggests ACVRL1 is associated with blood vessel development and repair.