Recombinant Human Arginase Protein (His & MYC Tag)

    • Recombinant Human Arginase Protein (His & MYC Tag)-Elabscience
    • Recombinant protein products for various applications-Elabscience
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    • Recombinant Human Arginase Protein (His & MYC Tag)-Elabscience
    • Recombinant protein products for various applications-Elabscience
    • Recombinant Human Arginase Protein (His & MYC Tag)-Elabscience
    • Recombinant protein products for various applications-Elabscience

      Catalog number:PKSH030301

      Synonyms:ARG1

      Size:
      • 10 µg
      • 50 µg
      Qty:
      - +
      Price: $454

      Lead Time: 7~10 daysWelcome to order from local distributors.

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      Overview

      Synonyms ARG1
      Species Human
      Expression_host HEK293 Cells
      Sequence Met 1-Lys 322
      Accession NP_000036.2
      Mol_Mass 36.7 kDa
      Tag N-His&C-MYC

      Properties

      Purity > 95 % as determined by reducing SDS-PAGE.
      Endotoxin < 1.0 EU per µg of the protein as determined by the LAL method.
      Storage Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
      Shipping This product is provided as lyophilized powder which is shipped with ice packs.
      Formulation Lyophilized from sterile 20 mM Tris, 500 mM NaCl, 20 % glycerol, pH 7.4
      Reconstitution Please refer to the printed manual for detailed information.

      Background

      Arginase is the focal enzyme of the urea cycle hydrolysing L-arginine to urea and L-ornithine. Emerging studies have identified arginase in the vasculature and have implicated this enzyme in the regulation of nitric oxide (NO) synthesis and the development of vascular disease. Arginase also redirects the metabolism of L-arginine to L-ornithine and the formation of polyamines and L-proline, which are essential for smooth muscle cell growth and collagen synthesis. Arginase is encoded by two recently discovered genes (Arginase I and Arginase II). In most mammals, Arginase 1 (ARG1) also known as Arginase, liver, which functions in the urea cycle, and is located primarily in the cytoplasm of the liver. The second isozyme, Arginase II, has been implicated in the regulation of the arginine/ornithine concentrations in the cell. It is located in mitochondria of several tissues in the body, with most abundance in the kidney and prostate. It may be found at lower levels in macrophages, lactating mammary glands, and brain.

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