Recombinant Human CD31 / PECAM1 Protein (Fc tag)

    • Recombinant Human CD31 / PECAM1 Protein (Fc tag)-Elabscience
    • Recombinant protein products for various applications-Elabscience
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    • Recombinant Human CD31 / PECAM1 Protein (Fc tag)-Elabscience
    • Recombinant protein products for various applications-Elabscience
    • Recombinant Human CD31 / PECAM1 Protein (Fc tag)-Elabscience
    • Recombinant protein products for various applications-Elabscience

      Catalog number:PKSH030454

      Synonyms:CD31;CD31/EndoCAM;endoCAM;GPIIA';PECA1;PECAM-1

      Size:
      • 100 µg
      • 200 µg
      Qty:
      - +
      Price: $486

      Lead Time: 7~10 daysWelcome to order from local distributors.

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      Overview

      Synonyms CD31;CD31/EndoCAM;endoCAM;GPIIA';PECA1;PECAM-1
      Species Human
      Expression_host HEK293 Cells
      Sequence Met 1-Lys 601
      Accession EAW94208.1
      Mol_Mass 91.2 kDa
      AP_Mol_Mass 130-140 kDa
      Tag C-Fc
      Bio_Activity Measured by the ability of the immobilized protein to support the adhesion of Jurkat human acute T cell leukemia cells. When 8 × 10E4 cells/well are added to sCD31-Fc coated plates (1.25μg/mL, 100μL/well) in the presence of 20ng/mL PMA, approximately 20-45% will adhere after 30 minutes at 37℃.

      Properties

      Purity > 95 % as determined by reducing SDS-PAGE.
      Endotoxin < 1.0 EU per µg as determined by the LAL method.
      Storage Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
      Shipping This product is provided as lyophilized powder which is shipped with ice packs.
      Formulation Lyophilized from sterile 100mM Glycine, 10mM NaCl, 50mM Tris, pH 7.5
      Reconstitution Please refer to the printed manual for detailed information.

      Background

      The Cluster of Differentiation 31 (CD31) adhesion molecule, also known as platelet-endothelial cell adhesion molecule-1 (PECAM-1), is the only known member of the CAM family on platelets. CD31 protein is a 130-kDa transmembrane glycoprotein expressed by endothelial cells, platelets, monocytes, neutrophils, and certain T cell subsets. CD31 protein is also expressed in certain tumors, including epithelioid hemangioendothelioma, other vascular tumors, and histiocytic malignancies. CD31 plays a key role in removing aged neutrophils and tissue regeneration. CD31 protein mediates the homotypic or heterotypic cell adhesion by binding to itself or the leukocyte integrin αvβ3, and thus plays a role in neutrophil recruitment in inflammatory responses, transendothelial migration of leukocytes, as well as in cardiovascular development.

      SDS-PAGE

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      MSDS for ELISA

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